Document Detail

Influence of metabolic risk factors on the presence of carotid artery disease in patients with type 2 diabetes and coronary artery disease.
MedLine Citation:
PMID:  17469044     Owner:  NLM     Status:  MEDLINE    
The aim of the study was to evaluate the prevalence of carotid artery disease in type 2 diabetes patients with coronary artery disease, and to establish the influence of metabolic factors on its occurrence. In all, 145 patients (aged 59.85+/-8.43 years, diabetes duration 8.89+/-6.29 years) were randomly selected in a cross-sectional study. Carotid ultrasound was used for evaluation of the presence of carotid plaque (CP) and stenosis (CS). A logistic regression model was constructed to define the influence of risk factors-- arterial hypertension, systolic blood pressure, weight, waist to hip ratio, high blood glucose and plasma lipid levels. Carotid artery disease was present in these patients with a prevalence of 81.9% for CP, 25.2% for unilateral CS and 13.5% for bilateral CS. The low-density lipoprotein (LDL) cholesterol level was an independent predictor for CS (OR 1.936; 95% CI 1.2413.026). Non-high density lipoprotein (HDL) cholesterol (OR 1.374; 95% CI 1.0351.825) and glycaemia (OR 1.214; 95% CI 1.0221.442) were predictors for carotid plaque.
Marijan Bosevski; Vladimir Borozanov; Ljubica Georgievska-Ismail
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Diabetes & vascular disease research : official journal of the International Society of Diabetes and Vascular Disease     Volume:  4     ISSN:  1479-1641     ISO Abbreviation:  -     Publication Date:  2007 Mar 
Date Detail:
Created Date:  2007-04-30     Completed Date:  2007-06-26     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  101234011     Medline TA:  Diab Vasc Dis Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  49-52     Citation Subset:  IM    
Institute for Heart Disease, Medical School Skopje, Skopje, Macedonia.
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MeSH Terms
Blood Glucose / metabolism
Blood Pressure
Carotid Artery Diseases / epidemiology,  etiology*
Coronary Artery Disease / complications*
Cross-Sectional Studies
Diabetes Mellitus, Type 2 / complications*,  physiopathology
Diabetic Angiopathies / epidemiology*
Lipid Metabolism
Middle Aged
Risk Factors
Reg. No./Substance:
0/Blood Glucose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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