Document Detail


Influence of meperidine on fetal movements and heart rate beat-to-beat variability in the active phase of labor.
MedLine Citation:
PMID:  3382477     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Eleven parturients were studied in the active phase of labor. Fetal movements, fetal heart rate, and short-term beat-to-beat variability as well as uterine contractions were evaluated for two 40-minute recording periods before and after maternal intravenous administration of 50 mg meperidine. Meperidine depressed fetal activity and increased the duration and frequency of uterine contractions. Fetal movements were significantly reduced from 156 to 60 and their relative duration from 8.6 +/- 6.0% to 2.4 +/- 2.6% (p less than 0.01). The short-term fetal heart rate beat-to-beat variability was reduced at the baseline period 5.22 +/- 1.02 versus 4.62 +/- 1.47 (p less than 0.05) but not during uterine contractions or fetal movements. The frequency of uterine contractions increased from 3.1 +/- 0.8 to 3.7 +/- 0.7 per 10 minutes (p less than 0.01), and their relative duration from 35.3 +/- 6.9% to 40.1 +/- 5.9% (p less than 0.05).
Authors:
E Z Zimmer; M Y Divon; A Vadasz
Related Documents :
16965227 - Fetal behavior analyzed by ultrasonic actocardiogram in cases with central nervous syst...
1946887 - Assessing attentional control of breathing by reaction time.
3061297 - Effect of third-trimester premature rupture of membranes on fetal breathing movements: ...
18980217 - Prenatal behavior of the c57bl/6j mouse: a promising model for human fetal movement dur...
6665057 - Attraction and repulsion by amniotic fluids and their olfactory control in the ewe arou...
11896527 - Caudal regression syndrome in twin pregnancy with type ii diabetes.
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  American journal of perinatology     Volume:  5     ISSN:  0735-1631     ISO Abbreviation:  Am J Perinatol     Publication Date:  1988 Jul 
Date Detail:
Created Date:  1988-08-09     Completed Date:  1988-08-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8405212     Medline TA:  Am J Perinatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  197-200     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology B, Rambam Medical Center, Haifa, Israel.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Drug Evaluation
Female
Fetal Movement / drug effects*
Heart Rate, Fetal / drug effects*
Humans
Labor, Obstetric / drug effects*
Meperidine / pharmacology*
Pregnancy
Uterine Contraction / drug effects
Chemical
Reg. No./Substance:
57-42-1/Meperidine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Determination of sotalol in human body fluids for pharmacokinetic and toxicokinetic studies using hi...
Next Document:  Cocaine use in pregnant women in a large public hospital.