| Influence of maternal dietary fat upon rat pups. | |
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MedLine Citation:
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PMID: 1147334 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Mother rats were fed purified rations containing different fats during gestation and lactation and at 1 day after parturition. Litter sizes were reduced to 2 male and 2 female pups. The behavior and the brain chemical composition of these selected pups were compared with similarly selected pups from dams fed a commercial ration. All offspring were fed a commercial ration after weaning. Pups from dams fed 20% safflower oil were similar to controls. Feeding 20% cocoa butter to dams resulted in pups with reduced exploratory activity and with a rapid learning performance in a T-maze, employing the aversive stimulation of an electrical shock. Feeding dams a fat-free ration produced pups which had reduced rates of growth, small brains at 2 months of age, and low brain concentrations of cholesterol, DNA, and RNA. |
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Authors:
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R F Borgman; R G Bursey; B C Caffrey |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: American journal of veterinary research Volume: 36 ISSN: 0002-9645 ISO Abbreviation: Am. J. Vet. Res. Publication Date: 1975 Jun |
Date Detail:
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Created Date: 1975-09-18 Completed Date: 1975-09-18 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0375011 Medline TA: Am J Vet Res Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 799-805 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Animals, Newborn* Avoidance Learning Behavior, Animal Body Weight Brain Chemistry Cacao Cholesterol / analysis DNA / analysis Dietary Fats / metabolism* Escape Reaction Exploratory Behavior Female Grooming Hair / growth & development Lactation Lipids / analysis Male Pregnancy RNA / analysis Rats / growth & development, metabolism* Safflower Oil / metabolism Weaning |
| Chemical | |
Reg. No./Substance:
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0/Dietary Fats; 0/Lipids; 57-88-5/Cholesterol; 63231-63-0/RNA; 8001-23-8/Safflower Oil; 9007-49-2/DNA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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