Document Detail

Influence of maternal anemia during pregnancy on placenta and newborns.
MedLine Citation:
PMID:  25195349     Owner:  NLM     Status:  In-Process    
INTRODUCTION: Sideropenic anemia is a common pregnancy disorder. Depending on severity, maternal anemia can significantly influence morphometric characteristic of placental tissue, pregnancy course and outcome.
OBJECTIVES: to estimate if maternal anemia a) results with significant placental changes; b) influence on newborn weight, length and vitality.
PATIENTS, MATERIAL AND METHODS: Research included 100 women and their newborns, 50 anemic, and 50 women in the control group. Sixty placentas were collected, placental mass and volume was determined, and blood vessels of terminal villi were stereologically analyzed. Newborns mass and body length, and Apgar scores within 1 and 5 minutes after delivery were recorded.
THE RESULTS: Placentas of anemic pregnant women showed significant increase of terminal villi blood vessels (224.18 vs. 197.00 cm3; p < 0.0001), but total placental mass and volume did not differ significantly. Anemic mothers' newborns were significantly shorter (51.76 vs. 55.54 cm; p < 0.0001), smaller body mass (3048.00 vs. 3615.60 g; p < 0.0001) and delivered one week early (38.2 vs. 39.2 GW; p < 0.0001), but not significantly poorer vitality (p > 0.05) comparing with the control group.
CONCLUSION: Sideropenic anemia increase placental maturity, that could be a possible cause of earlier spontaneous delivery among anemic women. The anemic mothers' newborns are shorter and lower body mass, but not poorer vitality index.
Melisa Lelic; Gordana Bogdanovic; Suada Ramic; Elvira Brkicevic
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Medicinski arhiv     Volume:  68     ISSN:  -     ISO Abbreviation:  Med Arh     Publication Date:  2014  
Date Detail:
Created Date:  2014-09-08     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0400722     Medline TA:  Med Arh     Country:  Bosnia and Hercegovina    
Other Details:
Languages:  eng     Pagination:  184-7     Citation Subset:  IM    
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