Document Detail


Influence of low-protein dietetic foods consumption on quality of life and levels of B vitamins and homocysteine in patients with chronic renal failure.
MedLine Citation:
PMID:  20449532     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The aim of the study was to determine whether the consumption of low protein dietetic foods improved the quality of life and nutritional status for vitamins B and homocysteine in patients with chronic renal failure.
METHODOLOGY: This nutritional-intervention involved 28 men and 21 women, divided into two groups. The control-group consumed a low-protein diet prescribed, and the experimental-group consumed a diet in which some commonly used foods were replaced by low-protein dietetic foods. The study lasted 6 months. Food consumption was assessed by 24-h recall. Vitamin B6 as alphaEAST was measured in blood. Creatinine, urea, vitamin B12, folate and homocysteine were measured in plasma. The impact on the patients' quality of life from consuming the dietetic foods was assessed via the SF-36 questionnaire.
RESULTS: After 6 months, the protein intake among the experimental-group had decreased by 40%, and the urea/creatinine ratio and alphaEAST activity were also lower. The results of the SF-36 questionnaire show that the patients in the experimental-group obtained higher scores in the categories of general health and physical status.
CONCLUSIONS: The dietetic foods were very well accepted by all patients and their use allowed a better control of the protein intake, improved B6 status and a better quality of life.
Authors:
C Sánchez; P Aranda; E Planells; P Galindo; A Pérez de la Cruz; M Larrubia; J Llopis
Publication Detail:
Type:  Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Nutrición hospitalaria     Volume:  25     ISSN:  0212-1611     ISO Abbreviation:  Nutr Hosp     Publication Date:    2010 Mar-Apr
Date Detail:
Created Date:  2010-05-07     Completed Date:  2010-07-20     Revised Date:  2013-07-02    
Medline Journal Info:
Nlm Unique ID:  9100365     Medline TA:  Nutr Hosp     Country:  Spain    
Other Details:
Languages:  eng     Pagination:  238-44     Citation Subset:  IM    
Affiliation:
Institute of Nutrition and Food Technology, Department of Physiology, Cartuja Campus, University of Granada, Granada, Spain. crissg@ugr.es
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MeSH Terms
Descriptor/Qualifier:
Diet, Protein-Restricted*
Female
Homocysteine / blood*
Humans
Kidney Failure, Chronic / blood*
Male
Middle Aged
Nutritional Status*
Quality of Life*
Vitamin B Complex / blood*
Chemical
Reg. No./Substance:
12001-76-2/Vitamin B Complex; 454-28-4/Homocysteine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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