Document Detail


Influence of lipoproteins and fibrinogen on pathogenesis of sudden sensorineural hearing loss.
MedLine Citation:
PMID:  21054908     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Aim:To evaluate the relationship between lipoproteins, fibrinogen and sudden sensorineural hearing loss in a Croatian population. Since pathological derangement of lipoproteins and fibrinogen could be one of the causes of sudden sensorineural hearing loss, we hypothesised that patients with sudden sensorineural hearing loss would have more abnormal fibrinogen and lipoprotein concentrations, compared with subjects with normal hearing.Methods:Plasma concentrations of cholesterol, fibrinogen and triglycerides in patients with sudden sensorineural hearing loss were compared with those in a control group (i.e. subjects with normal hearing function).Results:Patients with sudden sensorineural hearing loss had significantly higher plasma concentrations of cholesterol and low density lipoprotein cholesterol, compared with controls.Conclusion:Higher cholesterol and low density lipoprotein cholesterol concentrations were found in patients with sudden sensorineural hearing loss, within a Croatian population. Cholesterol and low density lipoprotein cholesterol concentrations may be important factors in the pathogenesis of sudden sensorineural hearing loss, and should be assessed during the investigation of patients with this condition.
Authors:
Z Oreskovic; D Shejbal; G Bicanic; B Kekic
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Publication Detail:
Type:  Journal Article     Date:  2010-11-05
Journal Detail:
Title:  The Journal of laryngology and otology     Volume:  125     ISSN:  1748-5460     ISO Abbreviation:  J Laryngol Otol     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-02-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8706896     Medline TA:  J Laryngol Otol     Country:  England    
Other Details:
Languages:  eng     Pagination:  258-61     Citation Subset:  AIM; IM    
Affiliation:
Department of Anesthesiology and Intensive Care, Clinical Hospital Center Zagreb, Zagreb, Croatia.
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