Document Detail

Influence of the k-space trajectory on the dynamic T1-weighted signal in quantitative first-pass cardiac perfusion MRI at 3T.
MedLine Citation:
PMID:  17957778     Owner:  NLM     Status:  MEDLINE    
The dynamic T(1)-weighted signal in first-pass myocardial perfusion MRI can vary as a function of k-space trajectory. The purpose of this study, therefore, was to compare the relative T(1)-weighted signal produced by the linear, centric, and reverse centric k-space trajectories at 3T. The centric k-space trajectory yielded higher arterial input function (AIF) than the linear and reverse centric k-space trajectories (6.21 +/- 0.84 vs. 4.75 +/- 0.75 vs. 4.39 +/- 0.85 mM, respectively; N = 9; P < 0.01), and the reverse centric k-space trajectory yielded higher myocardial signal contrast (as a fraction of equilibrium magnetization) than the linear and centric k-space trajectories (0.17 +/- 0.02 vs. 0.12 +/- 0.02 vs. 0.05 +/- 0.01, respectively; N = 9; P < 0.001). Compared to the linear k-space trajectory, the centric k-space trajectory is relatively optimal for the quantification of AIF, whereas the reverse centric k-space trajectory is relatively optimal for high contrast of myocardial wall enhancement.
Daniel Kim
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine     Volume:  59     ISSN:  0740-3194     ISO Abbreviation:  Magn Reson Med     Publication Date:  2008 Jan 
Date Detail:
Created Date:  2007-12-27     Completed Date:  2008-03-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8505245     Medline TA:  Magn Reson Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  202-8     Citation Subset:  IM    
Copyright Information:
2007 Wiley-Liss, Inc
Department of Radiology, New York University, New York, New York 10016, USA.
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MeSH Terms
Analysis of Variance
Contrast Media
Coronary Circulation / physiology*
Coronary Disease / physiopathology*
Gadolinium DTPA
Image Enhancement / methods*
Magnetic Resonance Imaging / methods*
Phantoms, Imaging
Reg. No./Substance:
0/Contrast Media; 80529-93-7/Gadolinium DTPA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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