| Influence of intraoperative opioid on postoperative pain and pulmonary function after laparoscopic gastric banding: remifentanil TCI vs sufentanil TCI in morbid obesity. | |
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MedLine Citation:
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PMID: 17606479 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Choice of opioid may influence postoperative pain, recovery, and respiratory homeostasis in morbid obesity. The aim of this study was to compare the effects of target-controlled infusions (TCIs) of remifentanil or sufentanil on postoperative analgesia, recovery, and pulmonary function after laparoscopic gastric banding. METHODS: Forty morbidly obese patients undergoing laparoscopic gastric banding received BIS-guided desflurane anaesthesia combined with remifentanil TCI (Group R) or sufentanil TCI (Group S). Intraoperative haemodynamic stability, BIS controllability, and immediate recovery in the operating room were measured. Pulmonary function, modified Aldrete score, modified Observers Assessment of Alertness and Sedation score, blood gas analysis, and visual analogue score for pain and postoperative nausea and vomiting were measured on admission to the post-anaesthesia care unit and 30, 60, 120 min afterwards. After operation, patients received patient-controlled analgesia with morphine. RESULTS: During the first two postoperative hours, cumulative morphine consumption was higher in the remifentanil group compared with the sufentanil group, but was equal values after that time. Recovery profiles and spirometry showed no significant differences. During maintenance, remifentanil gave a better haemodynamic stability. CONCLUSIONS: As few differences occurred in the postoperative period, the theoretical advantage of remifentanil over the longer acting sufentanil can be questioned when using TCI technology. |
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Authors:
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L E C De Baerdemaeker; S Jacobs; P Pattyn; E P Mortier; M M R F Struys |
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Publication Detail:
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Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't Date: 2007-07-02 |
Journal Detail:
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Title: British journal of anaesthesia Volume: 99 ISSN: 0007-0912 ISO Abbreviation: Br J Anaesth Publication Date: 2007 Sep |
Date Detail:
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Created Date: 2007-08-17 Completed Date: 2007-10-16 Revised Date: 2009-03-20 |
Medline Journal Info:
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Nlm Unique ID: 0372541 Medline TA: Br J Anaesth Country: England |
Other Details:
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Languages: eng Pagination: 404-11 Citation Subset: IM |
Affiliation:
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Department of Anaesthesia, Ghent University Hospital, Ghent, Belgium. luc.debaerdemaeker@ugent.be |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Analgesics, Opioid / administration & dosage, therapeutic use* Anesthesia Recovery Period Blood Pressure / drug effects Drug Administration Schedule Female Forced Expiratory Volume / drug effects Gastroplasty Heart Rate / drug effects Humans Male Middle Aged Morphine / administration & dosage Obesity, Morbid / surgery* Pain Measurement / methods Pain, Postoperative / drug therapy, prevention & control* Piperidines / administration & dosage, therapeutic use* Single-Blind Method Sufentanil / administration & dosage, therapeutic use* Vital Capacity / drug effects |
| Chemical | |
Reg. No./Substance:
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0/Analgesics, Opioid; 0/Piperidines; 132875-61-7/remifentanil; 56030-54-7/Sufentanil; 57-27-2/Morphine |
| Comments/Corrections | |
Comment In:
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Br J Anaesth. 2009 Mar;102(3):432-3; author reply 433
[PMID:
19218374
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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