Document Detail


Influence of inhaled procaterol on pulmonary rehabilitation in chronic obstructive pulmonary disease.
MedLine Citation:
PMID:  23199977     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a progressive condition that classically causes dyspnea during physical activity. Destruction of alveoli and bronchostenosis are thought to lead to shortness of breath and result in decreased physical activity. In this study, we examined the influence of inhaled procaterol on exercise therapy for pulmonary rehabilitation.
METHODS: Patients with moderate to severe stable COPD were randomly divided into 2 groups those who inhaled procaterol before exercise (n=10) and those who did not (control group) (n=11). For 12 weeks, all patients performed their pulmonary rehabilitation exercises at home. We measured the 6-minute walking distance (6MWD) to assess exercise tolerance and used St. George's respiratory questionnaire (SGRQ) to assess health-related quality of life (HRQOL) before and after the 12-week exercise program.
RESULTS: Compared to the control group, the group receiving inhaled procaterol showed significant improvement of 6MWD and SGRQ scores.
CONCLUSION: Our data suggest that a pulmonary rehabilitation program combined with inhaled procaterol can improve both HRQOL and exercise tolerance in COPD patients.
Authors:
Makoto Hasegawa; Kunio Dobashi; Takeo Horie; Naoki Wada; Kenji Shirakura
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Publication Detail:
Type:  Journal Article     Date:  2012-09-13
Journal Detail:
Title:  Respiratory investigation     Volume:  50     ISSN:  2212-5345     ISO Abbreviation:  Respir Investig     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101581124     Medline TA:  Respir Investig     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  135-9     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 The Japanese Respiratory Society. Published by Elsevier B.V. All rights reserved.
Affiliation:
Department of Rehabilitation, Gunma University Hospital, Japan. Electronic address: m.hasegawa@gunma-u.ac.jp.
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