Document Detail

Influence of hyperglycaemia on maximal gastric secretion in healthy subjects.
MedLine Citation:
PMID:  950083     Owner:  NLM     Status:  MEDLINE    
The influence of a single intravenous glucose load on maximal gastric acid secretion in 25 healthy men when stimulated with pentagastrin was studied. Under the influence of hyperglycaemia, a highly significant decrease of maximal acid output was found. Moreover, in the gastric juice an increase of chloride and calcium concentrations was noted. On the other hand, the output of potassium, chloride and magnesium was lowered. The above differences were statistically significant.
K Markiewicz; M Lukin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Digestion     Volume:  14     ISSN:  0012-2823     ISO Abbreviation:  Digestion     Publication Date:  1976  
Date Detail:
Created Date:  1976-10-02     Completed Date:  1976-10-02     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0150472     Medline TA:  Digestion     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  188-91     Citation Subset:  IM    
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MeSH Terms
Calcium / analysis
Chlorides / analysis
Gastric Acidity Determination
Gastric Juice / secretion*
Glucose / pharmacology
Hyperglycemia / physiopathology*
Magnesium / analysis
Pentagastrin / pharmacology
Potassium / analysis
Secretory Rate / drug effects
Sodium / analysis
Reg. No./Substance:
0/Chlorides; 50-99-7/Glucose; 5534-95-2/Pentagastrin; 7439-95-4/Magnesium; 7440-09-7/Potassium; 7440-23-5/Sodium; 7440-70-2/Calcium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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