| Influence of a history of smoking on short term (six month) clinical and angiographic outcome after successful coronary angioplasty. | |
| | |
MedLine Citation:
|
PMID: 10956296 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVES: To assess the influence of smoking on restenosis after coronary angioplasty. DESIGN AND PATIENTS: The incidence of smoking on restenosis was investigated in 2948 patients. They were prospectively enrolled in four major restenosis trials in which quantitative angiography was used before and immediately after successful angioplasty and again at six months. RESULTS: Within the study population there were 530 current smokers, 1690 ex-smokers, and 728 non-smokers. Smokers were more likely to be men (85.9% v 87. 5% v 65.3%, current v ex- v non-, p < 0.001), to be younger (54.0 (9. 0) v 57.0 (9.1) v 59.9 (9.4) years, p < 0.001), to have peripheral vascular disease (7.2% v 5.5% v 2.3%, p < 0.001), and have sustained a previous myocardial infarction (42.9% v 43.9% v 37.9%, p = 0.022), but were less likely to be diabetic (9.1% v 9.5% v 12.6%, p = 0.043) or hypertensive (24.9% v 29.3% v 37.2, p < 0.001). There was no significant difference in the categorical restenosis rate (> 50% diameter stenosis) at six months (35.28% v 35.33% v 37.09%, current v ex- v non-), or the absolute loss (0.29 (0.54) v 0.33 (0.52) v 0. 35 (0.55) mm, respectively; p = 0.172). CONCLUSIONS: Although smokers have a lower incidence of known predisposing risk factors for atherosclerosis, they require coronary intervention almost six years earlier than non-smokers and three years earlier than ex-smokers. Once they undergo successful coronary angioplasty, there appears to be no evidence that smoking influences their short term (six month) outcome, but because of the known long term effects of smoking, patients should still be encouraged to discontinue the habit. |
| | |
Authors:
|
A G Violaris; A Thury; E Regar; R Melkert; P W Serruys |
Related Documents
:
|
16492306 - Altered autonomic cardiac control predicts restenosis after percutaneous coronary inter... 12892766 - Predictors of late cardiac events following treatment with sr-90 beta-irradiation for i... 7872166 - Distal embolization is common after directional atherectomy in coronary arteries and sa... 18190986 - Treatment of diffuse in-stent restenosis with drug-eluting stents vs. intracoronary bet... 23601576 - Usefulness of monocyte chemoattractant protein-1 to predict no-reflow and three-year mo... 11530146 - Efficacy and safety of tenecteplase in combination with enoxaparin, abciximab, or unfra... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Heart (British Cardiac Society) Volume: 84 ISSN: 1468-201X ISO Abbreviation: Heart Publication Date: 2000 Sep |
Date Detail:
|
Created Date: 2000-09-19 Completed Date: 2000-09-19 Revised Date: 2009-11-18 |
Medline Journal Info:
|
Nlm Unique ID: 9602087 Medline TA: Heart Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 299-306 Citation Subset: AIM; IM |
Affiliation:
|
Academic Cardiology Unit, St Mary's Hospital, London W2, UK. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Age Factors Aged Angioplasty, Transluminal, Percutaneous Coronary* Coronary Angiography Coronary Disease / radiography, therapy* Disease-Free Survival Female Follow-Up Studies Humans Male Middle Aged Prospective Studies Recurrence Risk Factors Smoking / adverse effects* Statistics as Topic Time Factors |
| Comments/Corrections | |
Comment In:
|
Heart. 2000 Sep;84(3):233-4
[PMID:
10956278
]
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Prenatal diagnosis of congenital heart disease in the northern region of England: benefits of a trai...
Next Document: Clinical and angiographic outcome in patients with in-stent restenosis and repeat target lesion reva...