| Influence of hemorheological parameters and mean blood pressure on carotid blood flow asymmetry in patients with chronic unilateral cerebral infarctions. | |
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MedLine Citation:
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PMID: 20675905 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The study aimed to follow the influence of some hemorheological parameters and mean blood pressure (MBP) on the carotid blood flow asymmetry in 20 patients with chronic unilateral cerebral infarctions (UCI) as compared to 30 patients with transient ischemic attacks (TIAs), 17 patients with risk factors (RF) for cerebrovascular disease (CVD) and 11 healthy controls. Hemorheological variables: hematocrit (HT), plasma (PV) and whole blood viscosity (WBV), serum lipids and echocardiographic parameters were investigated. Blood pressure (systolic, diastolic and mean) was registered and color duplex sonography of the carotid arteries was performed. The lumen diameter, the intima media thickness (IMT) and the blood flow velocity (systolic, mean and diastolic) in the carotid arteries were examined and the velocity asymmetry ratio (AR) was calculated. Significant increase of HT in UCI, of mean blood pressure (MBP) in the patients with RF and TIAs and of IMT and velocity parameters in all patients was established. The correlation analysis revealed parallel influence of HT, MBP, cardiac function, IMT, lumen diameter and some of the modifiable RF on the carotid AR in patients with chronic UCI affecting mainly the collateral circulation. The complex investigation of these factors would enable us to individualize the therapeutic approach in the patients with cerebral ischemic events. |
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Authors:
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Irena Velcheva; Ekaterina Titianova; Nadia Antonova |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinical hemorheology and microcirculation Volume: 45 ISSN: 1875-8622 ISO Abbreviation: Clin. Hemorheol. Microcirc. Publication Date: 2010 |
Date Detail:
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Created Date: 2010-08-02 Completed Date: 2010-12-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9709206 Medline TA: Clin Hemorheol Microcirc Country: Netherlands |
Other Details:
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Languages: eng Pagination: 239-44 Citation Subset: IM |
Affiliation:
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Department of Neurology, Medical University, Sofia, Bulgaria. velchevairena@gmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Blood Flow Velocity Blood Pressure* Blood Viscosity Carotid Arteries / physiopathology*, ultrasonography Case-Control Studies Cerebral Infarction / blood* Chronic Disease Electrocardiography Female Hematocrit Hemorheology* Humans Ischemic Attack, Transient / blood Lipids / blood Male Middle Aged |
| Chemical | |
Reg. No./Substance:
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0/Lipids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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