Document Detail

Influence of gestational hormones on Trypanosoma musculi infection of the mouse.
MedLine Citation:
PMID:  3384074     Owner:  NLM     Status:  MEDLINE    
When mice were infected with Trypanosoma musculi during the second week of pregnancy, the level of parasitemia was significantly higher than in controls. Progesterone and estradiol injected daily into normal virgin mice during the course of infection did not modify the parasitemia. Daily injections of low-dose hydrocortisone into infected mice produced elevated parasitemias although these never reached the levels obtained during pregnancy. It is postulated that systemic levels of gestational hormones are only a minor contributing factor for elevated parasitemia.
M Lussier; P Viens
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Experimental biology     Volume:  47     ISSN:  0176-8638     ISO Abbreviation:  Exp Biol     Publication Date:  1988  
Date Detail:
Created Date:  1988-08-11     Completed Date:  1988-08-11     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  8503247     Medline TA:  Exp Biol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  183-4     Citation Subset:  IM    
Department of Microbiology and Immunology, Faculty of Medicine, University of Montreal, Quebec, Canada.
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MeSH Terms
Estradiol / physiology
Hydrocortisone / pharmacology
Mice, Inbred CBA
Placenta / immunology
Pregnancy Complications, Infectious / immunology*
Progesterone / physiology
Trypanosomiasis / immunology*
Reg. No./Substance:
50-23-7/Hydrocortisone; 50-28-2/Estradiol; 57-83-0/Progesterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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