Document Detail

Influence of gender on mortality and need for extracorporeal membrane oxygenation in neonates with congenital diaphragmatic hernia.
MedLine Citation:
PMID:  22523303     Owner:  NLM     Status:  In-Data-Review    
PATIENTS AND METHODS: All parturients with newborns suffering from CDH were included. A total of 425 infants with CDH were analyzed. The primary outcome parameters evaluated were the necessity of ECMO and the survival. Secondary outcome parameters were the mode of delivery, the arterial umbilical cord pH value, the Apgar score, and the postpartum day of death. Cases with incomplete data were excluded.
RESULTS: An analysis of the gender distribution of neonates in our study revealed that more males (n=248) than females (n=177) suffered from CDH. This represented a male versus female gender ratio of 58.4% to 41.6%, a significantly different ratio from that for neonates without CDH (p=0.003). Comparing both groups, statistical analysis showed no significant differences in mode of delivery, arterial umbilical cord blood pH, Apgar score, or CDH-relevant parameters of postpartum survival, including the need for ECMO therapy.
CONCLUSION: CDH occurred significantly more frequently in male newborns. However, there were no significant differences in postnatal survival nor in the necessity of ECMO therapy.
Sebastian Berlit; Amadeus Hornemann; Thomas Schaible; Wolfgang Neff; Regine Schaffelder; Jörn Siemer; Marc Sütterlin; Sven Kehl
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  In vivo (Athens, Greece)     Volume:  26     ISSN:  1791-7549     ISO Abbreviation:  In Vivo     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-04-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8806809     Medline TA:  In Vivo     Country:  Greece    
Other Details:
Languages:  eng     Pagination:  481-6     Citation Subset:  IM    
University Medical Center Mannheim, Department of Obstetrics and Gynecology, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.
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