Document Detail


Influence of gender and age on cognitive inhibition in late-onset depression: a case-control study.
MedLine Citation:
PMID:  23303735     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVE: To compare cognitive inhibition performance between people with early-onset (EOD) or late-onset depression (LOD) and controls, and between women and men with LOD. METHODS: On the basis of a case-control design, global executive performance (Frontal Assessment Battery); verbal (Hayling), attention (Stroop), and motor (Go/No-Go) components of cognitive inhibition; mental shifting (Trail Making Test parts A and B); and updating in working memory (Wechsler Adult Intelligence Scale) were assessed in 40 participants (10 depressed women with LOD (i.e., ≥60 years old), 10 depressed women with EOD (i.e., <60 years old), 10 healthy women and 10 depressed men with LOD (i.e., ≥60 years old)). RESULTS: Older depressed women, irrespective of age of depression onset, had greater cognitive inhibition impairments (attention and verbal component) compared with healthy women. LOD was significantly associated with the attention component of cognitive inhibition impairment, unlike EOD (p = 0.026). No executive differences were found regarding age of first-onset depression in older depressed women, and between women and men with LOD. CONCLUSION: Cognitive inhibition impairment, and more specifically its attention component, was the main characteristic of depression in the studied sample of older adults, independently of gender and age of depression onset. It is essential to perform similar studies in both genders in view of future tailor-made therapeutic modalities. Copyright © 2013 John Wiley & Sons, Ltd.
Authors:
S Richard-Devantoy; F Deguigne; C Annweiler; G Letourneau; O Beauchet
Related Documents :
16563155 - Anxiety and stress in the postpartum: is there more to postnatal distress than depression?
11982545 - Changes in the rate of diagnosis of major depression in adolescents following routine u...
23583855 - Lower csf interleukin-6 predicts future depression in a population-based sample of olde...
18089645 - Translation, validation and cultural aspects of postpartum depression screening scale i...
497625 - Hostility and guilt in obsessive-compulsive neurosis.
21530715 - Association of antidepressant medication therapy with inpatient rehabilitation outcomes...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-10
Journal Detail:
Title:  International journal of geriatric psychiatry     Volume:  -     ISSN:  1099-1166     ISO Abbreviation:  Int J Geriatr Psychiatry     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8710629     Medline TA:  Int J Geriatr Psychiatry     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2013 John Wiley & Sons, Ltd.
Affiliation:
McGill University, Department of Psychiatry and Douglas Mental Health University Institute McGill Group for Suicide Studies, Montréal, QC, Canada; Laboratoire de Psychologie des Pays de la Loire, UPRES EA 4638, Université d'Angers, Angers, France.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Chondrogenic potential of injectable??-carrageenan hydrogel with encapsulated adipose stem cells for...
Next Document:  Lighting up GPCRs with a Fluorescent Multiprobe Dubbed "Snifit"