Document Detail


Influence of food on bioavailability of amdinocillin pivoxil.
MedLine Citation:
PMID:  3377469     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The bioavailability of amdinocillin was not altered when amdinocillin pivoxil was ingested 1 h before a standard breakfast, and it increased by 20% when amdinocillin pivoxil was ingested with or 1 h after a standard breakfast. Amdinocillin pivoxil would be convenient for patients since it may be taken with or without food.
Authors:
L D Bornemann; S Castellano; A H Lin; D Enthoven; I H Patel
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Antimicrobial agents and chemotherapy     Volume:  32     ISSN:  0066-4804     ISO Abbreviation:  Antimicrob. Agents Chemother.     Publication Date:  1988 Apr 
Date Detail:
Created Date:  1988-06-27     Completed Date:  1988-06-27     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0315061     Medline TA:  Antimicrob Agents Chemother     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  592-4     Citation Subset:  IM    
Affiliation:
Pharmaceutical Research and Development, Hoffmann-La Roche Inc., Nutley, New Jersey 07110.
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MeSH Terms
Descriptor/Qualifier:
Administration, Oral
Adult
Amdinocillin / blood,  pharmacokinetics*,  urine
Amdinocillin Pivoxil / adverse effects,  pharmacokinetics*
Biological Availability
Chromatography, High Pressure Liquid
Female
Food*
Humans
Male
Middle Aged
Random Allocation
Chemical
Reg. No./Substance:
32886-97-8/Amdinocillin Pivoxil; 32887-01-7/Amdinocillin
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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