| Influence of food on absorption of erythromycin ethyl succinate. | |
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MedLine Citation:
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PMID: 6969579 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Erythromycin plasma concentrations were determined in 18 subjects after a single dose (800 mg) of a new formulation of erythromycin ethyl succinate taken immediately before, immediately after, and 1 h after food. Adequate absorption occurred with all treatments, although bioavailability was best when the drug was taken before food. Absorption was delayed by food, with the highest and earliest peak plasma erythromycin levels occurring under fasting conditions. |
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Authors:
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P J Thompson; K R Burgess; G E Marlin |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Antimicrobial agents and chemotherapy Volume: 18 ISSN: 0066-4804 ISO Abbreviation: Antimicrob. Agents Chemother. Publication Date: 1980 Nov |
Date Detail:
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Created Date: 1981-02-19 Completed Date: 1981-02-19 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0315061 Medline TA: Antimicrob Agents Chemother Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 829-31 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Erythromycin / analogs & derivatives*, metabolism Erythromycin Ethylsuccinate Food* Humans Intestinal Absorption* Kinetics Male |
| Chemical | |
Reg. No./Substance:
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114-07-8/Erythromycin; 1264-62-6/Erythromycin Ethylsuccinate |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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