Document Detail


Influence of fetal and parental factors on intra-uterine growth measurements: results of the EDEN mother-child cohort.
MedLine Citation:
PMID:  21438052     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVES: In small-for-gestational-age neonates, parental and fetal characteristics can be used to distinguish between constitutionally small size and growth restriction, which is associated with higher risk of morbidity and mortality. Relationships between parental and fetal characteristics and fetal ultrasound measurements have been little investigated. The aim of this study was to quantify these relationships. METHODS: The EDEN mother-child cohort included 2002 pregnant women with singleton pregnancies attending two university hospitals. Data from two routine ultrasound examinations for fetal biometry were recorded, at 20 to 25 and 30 to 35 weeks of gestation (WG). Biparietal diameter (BDP), head circumference (HC), femur length (FL), abdominal circumference (AC) and estimated fetal weight (EFW) were studied as a function of pre-pregnancy maternal body mass index (BMI), maternal height, paternal height, fetal sex, and gestational age. RESULTS: Data were obtained for the first scan for 1833 women and for the second scan for 1752 women. Parental anthropometric characteristics were significantly associated with ultrasound measurements at both scans. Maternal BMI was more strongly associated with AC and EFW, whereas parental height was more strongly associated with FL. An association was also found between fetal sex and all ultrasound measurements other than FL. CONCLUSION: Maternal and paternal anthropometric characteristics are significantly associated with ultrasound measurements early in pregnancy. These relationships provide support for the use of these characteristics in ultrasound fetal size reference charts. Copyright © 2011 ISUOG. Published by John Wiley & Sons, Ltd.
Authors:
M Albouy-Llaty; O Thiebaugeorges; V Goua; G Magnin; M Schweitzer; A Forhan; N Lelong; R Slama; M A Charles; M Kaminski;
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-3-22
Journal Detail:
Title:  Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology     Volume:  -     ISSN:  1469-0705     ISO Abbreviation:  -     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-3-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9108340     Medline TA:  Ultrasound Obstet Gynecol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 ISUOG. Published by John Wiley & Sons, Ltd.
Affiliation:
INSERM, UMR S 953, IFR69, Epidemiological research on perinatal health and women's and children's health, F-94807, Villejuif, France; Public Health and Pharmacy Department, University Hospital of Poitiers. marion.llaty@univ-poitiers.fr.
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