| Influence of fermentable fiber on small intestinal dimensions and transport of glucose and proline in dogs. | |
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MedLine Citation:
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PMID: 10188819 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To determine whether intestinal dimensions and nutrient absorption are influenced by different types of dietary fiber. ANIMALS: 10 adult Beagles of both sexes. PROCEDURE: Dogs were randomly assigned to 2 groups and fed a diet with fermentable fibers (beet pulp and oligofructose) or a nonfermentable fiber (cellulose) for 6 weeks. Effects of the diets on small intestinal dimensions were measured, and transport rates for glucose and proline were determined. Kinetics of glucose and proline uptake were defined in the proximal and middle regions of the small intestine, respectively. RESULTS: Small intestines of dogs fed fermentable fiber had 28% more nominal surface area and 37% more mucosal mass, were 35% heavier, and had 95% higher capacity for carrier-mediated glucose uptake than those of dogs fed a diet with cellulose. Differences were more pronounced in the proximal portion of the intestine. CONCLUSIONS AND CLINICAL RELEVANCE: Diets containing fermentable fibers increase small intestinal dimensions and the capacity for nutrient absorption in dogs. These changes may reduce the risk of enteric infections or aid in treatment of intestinal diseases, particularly those involving reduced nutrient absorption. |
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Authors:
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R K Buddington; K K Buddington; G D Sunvold |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: American journal of veterinary research Volume: 60 ISSN: 0002-9645 ISO Abbreviation: Am. J. Vet. Res. Publication Date: 1999 Mar |
Date Detail:
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Created Date: 1999-05-25 Completed Date: 1999-05-25 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0375011 Medline TA: Am J Vet Res Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 354-8 Citation Subset: IM |
Affiliation:
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Department of Biological Sciences, Mississippi State University, Mississippi State 39762, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Absorption Animals Biological Transport Dietary Fiber / pharmacology* Dogs / metabolism* Female Fermentation* Glucose / metabolism* Intestine, Small / physiology* Kinetics Male Proline / metabolism* |
| Chemical | |
Reg. No./Substance:
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147-85-3/Proline; 50-99-7/Glucose |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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