Document Detail

Influence of eye movements on Rett stereotypies: evidence suggesting a stage-specific regression.
MedLine Citation:
PMID:  9568758     Owner:  NLM     Status:  MEDLINE    
The influence of eye movements on hand use and pervasive stereotypies in Rett syndrome was studied, to better understand the developmental abnormality in this disorder. Nine patients in the post-regression phase were offered objects. As expected, the girls looked at the objects but usually did not reach for them. Nor were their characteristic hand stereotypies altered by such looking. But the occurrence of stereotypies was promoted by overall shifts in gaze, ie, eye movements in any direction. This finding may be relevant to the late-infancy loss of voluntary hand use in Rett syndrome associated with onset of pervasive stereotypies. It suggests a stage-specific regression to a level characteristic of normal 3-month-old infants who do not reach and grasp, but whose hand clasping and mouthing may be triggered by the perceptual consequences of exploratory eye movements and shifts in gaze.
R Umansky; J S Watson
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of child neurology     Volume:  13     ISSN:  0883-0738     ISO Abbreviation:  J. Child Neurol.     Publication Date:  1998 Apr 
Date Detail:
Created Date:  1998-06-10     Completed Date:  1998-06-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8606714     Medline TA:  J Child Neurol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  158-62     Citation Subset:  IM    
Child Development Center, Children's Hospital Oakland, CA 94609, USA.
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MeSH Terms
Child, Preschool
Eye Movements / physiology*
Motor Skills*
Rett Syndrome / physiopathology*
Stereotyped Behavior / physiology
Visual Perception

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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