| Influence of exogenous interleukin-2 concentration on the isolation of human immunodeficiency virus. | |
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MedLine Citation:
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PMID: 7783684 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A significant increase (P = 0.015) in the HIV isolation rate from plasma samples was achieved by use of 10 U/ml exogenous interleukin-2 compared to 20 U/ml. The sensitivity rose from 0% to 29% in patients negative for p24 core antigen (P = 0.031) and from 71% to 86% in patients positive for p24 core antigen in plasma (P > 0.05). Titration of infectious HIV revealed that 10 U/ml interleukin-2 is the optimal concentration to isolate low numbers of infectious particles of HIV. |
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Authors:
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B Zöllner; H H Feucht; A Hamann; R Laufs |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Microbiology and immunology Volume: 39 ISSN: 0385-5600 ISO Abbreviation: Microbiol. Immunol. Publication Date: 1995 |
Date Detail:
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Created Date: 1995-07-20 Completed Date: 1995-07-20 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7703966 Medline TA: Microbiol Immunol Country: JAPAN |
Other Details:
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Languages: eng Pagination: 117-21 Citation Subset: IM; X |
Affiliation:
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Institut für Medizinische Mikrobiologie und Immunologie, Universitätsklinikum Eppendorf, Hamburg, Germany. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acquired Immunodeficiency Syndrome
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blood,
microbiology Cells, Cultured DNA, Viral / analysis Enzyme-Linked Immunosorbent Assay Flow Cytometry HIV Core Protein p24 / analysis HIV Infections / blood*, microbiology HIV-1 / genetics, growth & development, isolation & purification* Humans Interleukin-2 / pharmacology* Leukocytes, Mononuclear / drug effects, microbiology* Microbiological Techniques Polymerase Chain Reaction Sensitivity and Specificity Viremia / microbiology |
| Chemical | |
Reg. No./Substance:
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0/DNA, Viral; 0/HIV Core Protein p24; 0/Interleukin-2 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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