Document Detail

Influence of exercise training on left ventricular diastolic function and its relationship to exercise capacity in patients after myocardial infarction.
MedLine Citation:
PMID:  20544611     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The study's aim was to examine the effect of exercise training on left ventricular diastolic function (LVDF) and whether LVDF could predict an improvement in exercise capacity (EC) in post-myocardial infarction patients. METHODS: Forty-eight males, aged 56.4 +/- 7.2 years, with preserved left ventricular systolic function (LVSF) and mild diastolic dysfunction (the ratio of transmitral early left ventricular filling velocity to early diastolic mitral annulus velocity E/E' > 8 as the average of the septal and lateral annulus velocities), were assigned to either a training group (TG, n = 32) or controls (n = 16). Before, and at the end of the study, all patients underwent a cardiopulmonary test and echocardiography with tissue Doppler imaging (TDI). RESULTS: After a 4.5-month training program, maximal oxygen consumption increased significantly in TG (26.66 +/- 3.88 vs. 28.79 +/- 5.00 mL/kg/min, p < 0.0001). TDI-derived E/E' did not change after the training program. After dividing TG according to septal E/E's > 10 and < 10 and lateral E/E'l > 8 and < 8, exercise capacity improved significantly only in patients with E/E's < 10 and E/E'l < 8. CONCLUSIONS: A 4.5-month training program in post-myocardial infarction patients with preserved LVSF and mild diastolic dysfunction led to improved exercise capacity only in TG. The diastolic function did not change significantly. The improvement in exercise capacity was significantly greater in patients with a better LVDF measured by TDI.
Iwona Korzeniowska-Kubacka; Maria Bilińska; Ewa Michalak; Beata Kuśmierczyk-Droszcz; Barbara Dobraszkiewicz-Wasilewska; Ryszard Piotrowicz
Publication Detail:
Type:  Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Cardiology journal     Volume:  17     ISSN:  1897-5593     ISO Abbreviation:  Cardiol J     Publication Date:  2010  
Date Detail:
Created Date:  2010-06-14     Completed Date:  2010-09-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101392712     Medline TA:  Cardiol J     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  136-42     Citation Subset:  IM    
Department of Cardiac Rehabilitation and Noninvasive Electrocardiology, Institute of Cardiology, Warszawa, Poland.
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MeSH Terms
Blood Pressure
Echocardiography, Doppler
Exercise Test
Exercise Therapy*
Exercise Tolerance*
Heart Rate
Middle Aged
Myocardial Infarction / complications,  diagnosis,  physiopathology,  rehabilitation*
Oxygen Consumption
Recovery of Function
Time Factors
Treatment Outcome
Ventricular Dysfunction, Left / diagnosis,  etiology,  physiopathology,  rehabilitation*
Ventricular Function, Left*
Comment In:
Cardiol J. 2010;17(2):115-6   [PMID:  20544608 ]

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