Document Detail


Influence of exercise intensity on abdominal fat and adiponectin in elderly adults.
MedLine Citation:
PMID:  19196080     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To examine the influence of moderate-intensity (50% of VO(2peak)) exercise training (MI) versus high-intensity (75% of VO(2peak)) exercise training (HI) on regional fat distribution and plasma adiponectin, we randomized 18 overweight (body mass index [BMI] = 30 +/- 1 kg/m(2)) elderly (71 +/- 1 years) to HI, MI, or a control group (CON). Subjects enrolled in HI or MI completed a 12-week exercise training protocol designed to expend 1000 kcal/week. Body composition testing was completed prior to and following the exercise training using dual energy X-ray absorptiometry and a computed tomography scan. Plasma adiponectin was measured using enzymelinked immunoassay (ELISA). VO(2peak) improved in HI and MI, whereas there was no change in VO(2peak) in CON. No significant change in body weight, BMI, and % fat occurred in MI, HI, or CON. Although there was a significant reduction in visceral fat with HI (-39 cm(2)), there was no change in the MI or CON groups. In addition, there was a significant increase in thigh muscle attenuation in the HI group. There were no changes in thigh muscle attenuation in the MI and CON groups. Also, there was no change in plasma adiponectin in the MI, HI, or CON groups. In summary, our direct comparison of exercise intensity without weight loss promotes the efficacy of HI in the reduction in visceral fat, even without changes in adiponectin.
Authors:
Robert H Coker; Rick H Williams; Patrick M Kortebein; Dennis H Sullivan; William J Evans
Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Metabolic syndrome and related disorders     Volume:  7     ISSN:  1557-8518     ISO Abbreviation:  Metab Syndr Relat Disord     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2009-08-04     Completed Date:  2009-11-16     Revised Date:  2011-08-01    
Medline Journal Info:
Nlm Unique ID:  101150318     Medline TA:  Metab Syndr Relat Disord     Country:  United States    
Other Details:
Languages:  eng     Pagination:  363-8     Citation Subset:  IM    
Affiliation:
Department of Geriatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA. cokerrobert@uams.edu
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MeSH Terms
Descriptor/Qualifier:
Abdominal Fat / metabolism*
Adiponectin / blood,  metabolism*
Aged
Aged, 80 and over
Body Mass Index
Body Weight
Enzyme-Linked Immunosorbent Assay
Exercise*
Female
Humans
Intra-Abdominal Fat
Male
Muscles / pathology
Obesity
Oxygen Consumption
Spectrometry, X-Ray Emission / methods
Tomography, X-Ray Computed / methods
Grant Support
ID/Acronym/Agency:
K01 DK 64716-01/DK/NIDDK NIH HHS; M01 RR14288/RR/NCRR NIH HHS; R01 AG 19346-01/AG/NIA NIH HHS
Chemical
Reg. No./Substance:
0/Adiponectin
Comments/Corrections

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