Document Detail


Influence of embedding media in prolactin labelling with immunogold techniques.
MedLine Citation:
PMID:  3536804     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Immunogold labelling of prolactin in three different embedding media was compared. The polymeric prolactin in secretory granules was labelled in the three media, however, acrylic monomers (Lowicryl K4M and LR White) provided a more intense labelling with higher dilutions of the primary antibody, compared to the labelling in the epoxy resin (araldite). An intense labelling of monomeric prolactin in Golgi complex was detected only in acrylic embedments, and the labelling on the rough endoplasmic reticulum was significant only in LR White embedded tissues.
Authors:
C A Maldonado; A Aoki
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Histochemical journal     Volume:  18     ISSN:  0018-2214     ISO Abbreviation:  Histochem. J.     Publication Date:  1986 Aug 
Date Detail:
Created Date:  1987-01-05     Completed Date:  1987-01-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0163161     Medline TA:  Histochem J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  429-33     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Acrylic Resins*
Animals
Epoxy Resins*
Female
Gold
Histocytochemistry
Immunologic Techniques
Phthalic Acids*
Phthalic Anhydrides*
Pituitary Gland / analysis
Prolactin / analysis*
Rats
Rats, Inbred Strains
Chemical
Reg. No./Substance:
0/Acrylic Resins; 0/Epoxy Resins; 0/Phthalic Acids; 0/Phthalic Anhydrides; 37226-48-5/araldite; 7440-57-5/Gold; 84137-04-2/Lowicryl 4KM resin; 9002-62-4/Prolactin; 94188-59-7/LR white

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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