| Influence of early (F+0) intravenous furosemide injection on the split renal function using 99mTc-DTPA renography. | |
| | |
MedLine Citation:
|
PMID: 23376860 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
In busy nuclear medicine departments, the F+0 protocol for diuretic renography is routinely used to shorten the acquisition time. The aim of this study was to evaluate the influence of the F+0 protocol on the split renal function (SRF) during a dynamic renal scan using technetium-99m diethylene triamine pentaacetic acid (Tc-DTPA) compared with that using the standard technetium-99m dimercaptosuccinic acid (Tc-DMSA). A total of 102 patients referred for a dynamic renal scan for varied etiologies were divided into two groups: the F+0 group, comprising 53 patients who were injected with furosemide just before Tc-DTPA injection, and the F+10 group, comprising 49 patients who were injected with the diuretic at the 10th minute after radiotracer injection. All patients were also subjected to a static cortical Tc-DMSA scan with geometric quantification of SRF. A highly significant statistical difference (P<0.001) was obtained on comparing the mean value of the difference in SRF calculated using DTPA and DMSA between the F+0 and F+10 groups, being 5.0±2.6 and 1.5±0.6%, respectively. All 49 patients in the F+10 group had a difference in split function of 5% or less, whereas 17/53 patients representing 32.1% of the F+0 group had a difference in SRF of greater than 5%. Early (F+0) furosemide injection before administration of Tc-DTPA has a significant influence on the estimation of SRF of the diseased kidney (either obstructed or functionally impaired) when compared with furosemide injection after standard Tc-DMSA administration. Care should be taken during interpretation of the scan findings when accurate split function is required. |
| | |
Authors:
|
Ahmed A Kandeel; Salwa A Elhossainy; Nahla D Elsayed |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2013-1-30 |
Journal Detail:
|
Title: Nuclear medicine communications Volume: - ISSN: 1473-5628 ISO Abbreviation: Nucl Med Commun Publication Date: 2013 Jan |
Date Detail:
|
Created Date: 2013-2-4 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8201017 Medline TA: Nucl Med Commun Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Department of Nuclear Medicine, Kasr Al-Einy Hospital, Cairo University, Cairo, Egypt. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Diagnostic role of 18F-dihydroxyphenylalanine positron emission tomography in patients with congenit...
Next Document: Prognostic value of myocardial perfusion imaging for cardiovascular events among asymptomatic Japane...