Document Detail


Influence of different medium components on the in vitro activity of the growth-promoting antibiotic flavomycin against enterococci.
MedLine Citation:
PMID:  11062189     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The growth-promoting antibiotic flavomycin (also called bambermycin, flavophospholipol and moenomycin) has a complex spectrum of activity against enterococci, with some species being naturally resistant and others susceptible. In this study, proteins added to Mueller-Hinton II medium had a strong deleterious effect on the activity of flavomycin, glucose had no effect and starch decreased the activity of flavomycin. The fatty substances Tween 80 and tributyrin increased the activity of flavomycin for several enterococcal species. Slight differences in the composition of the susceptibility test medium affected the MIC results obtained, indicating that strict standardization of the test medium is necessary.
Authors:
P Butaye; L A Devriese; F Haesebrouck
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of antimicrobial chemotherapy     Volume:  46     ISSN:  0305-7453     ISO Abbreviation:  J. Antimicrob. Chemother.     Publication Date:  2000 Nov 
Date Detail:
Created Date:  2001-02-06     Completed Date:  2001-02-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7513617     Medline TA:  J Antimicrob Chemother     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  713-6     Citation Subset:  IM    
Affiliation:
Laboratory of Veterinary Bacteriology and Mycology, Department of Pathology, Bacteriology and Poultry Diseases, Faculty of Veterinary Medicine, University of Ghent, Merelbeke, Belgium. pbutaye@allserv.rug.ac.be
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MeSH Terms
Descriptor/Qualifier:
Animals
Anti-Bacterial Agents / pharmacology*
Bacteriological Techniques / methods
Bambermycins / pharmacology*
Culture Media / chemistry,  pharmacology*
Drug Resistance, Microbial / physiology
Enterococcus / drug effects*
Microbial Sensitivity Tests / methods
Species Specificity
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Culture Media; 11015-37-5/Bambermycins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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