| Influence of different dietary levels of zinc on performance, vitamin B12, and blood parameters in lambs. | |
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MedLine Citation:
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PMID: 17607954 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This experiment was conducted to investigate the influence of different dietary levels of zinc (Zn) on performance, vitamin B12, and blood parameters in lambs. Thirty six cannulated Poll Dorset x Small-tailed Han wether lambs were assigned randomly to four treatment groups: The control group, which was supplemented with 0.30 mg Co/kg dry matter (DM) to the basal diet; and the low-, medium- and high-Zn supplemented groups, supplementation of 50, 100, and 150 mg Zn/kg DM to the control diet, respectively. Lambs were housed in individual pens and the experiment lasted for 70 days. There was no significant difference in body weight gain and feed/gain between different treatment groups. The high-Zn supplemented lambs showed lower vitamin B12 concentrations in both ruminal fluid and plasma, and higher methylmalonic acid and homocysteine concentrations in plasma compared with the control and low-Zn supplemented groups (p < 0.05). No significant difference was observed in these biochemical values between the control, the low-, and the medium-Zn supplemented groups (p > 0.05). Plasma folate concentration, glucose, and heme-dependent blood parameters were not influenced by dietary zinc level. It was concluded that the higher level of zinc supplementation had a negative effect on vitamin B12 in lambs. Higher inclusion level of dietary zinc could inhibit vitamin B12 synthesis in the rumen of lambs. |
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Authors:
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Runlian Wang; Xiaoping Zhu; Fucun Guo; Wei Zhang; Zhihai Jia |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition Volume: 76 ISSN: 0300-9831 ISO Abbreviation: Int J Vitam Nutr Res Publication Date: 2006 Nov |
Date Detail:
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Created Date: 2007-07-04 Completed Date: 2007-08-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 1273304 Medline TA: Int J Vitam Nutr Res Country: Switzerland |
Other Details:
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Languages: eng Pagination: 353-8 Citation Subset: IM |
Affiliation:
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College of Animal Science and Technology, China Agricultural University, Beijing 100094, P R China. wangrunlian2005@yahoo.com.cn |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animal Feed* Animals Blood Glucose / drug effects Body Weight / drug effects* Cobalt / administration & dosage Diet / methods* Dietary Supplements Dose-Response Relationship, Drug Folic Acid / blood, drug effects Homocysteine / blood, drug effects Methylmalonic Acid / blood Rumen / drug effects, metabolism Sheep Vitamin B 12 / blood, metabolism* Zinc / adverse effects, pharmacology* |
| Chemical | |
Reg. No./Substance:
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0/Blood Glucose; 454-28-4/Homocysteine; 516-05-2/Methylmalonic Acid; 59-30-3/Folic Acid; 68-19-9/Vitamin B 12; 7440-48-4/Cobalt; 7440-66-6/Zinc |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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