Document Detail

Influence of dietary taurine on vitamin D absorption.
MedLine Citation:
PMID:  8241636     Owner:  NLM     Status:  MEDLINE    
To evaluate the influence of dietary taurine supplementation on vitamin D absorption, we studied three groups of infants: 21 (11 preterm) were fed a taurine-free formula, 21 (10 preterm) were fed a taurine-supplemented formula (50 mg/100 g of powder) and 20 (9 preterm) were fed human, not heat-treated milk. Taurine, total bile acids, glyco-(GBA) and tauro-(TBA) conjugated bile acids, 25-hydroxyvitamin D3 (25OHD3) and 1,25-dihydroxyvitamin D3 (1,25OH2D3) were determined in all infants at birth in blood cord and at one and three months of life. In preterm infants fed a taurine-free formula, we found lower plasma taurine levels than in infants of other groups at one and three months of life. In these infants, GBA predominated, with a G/T ratio of 1.1 and 1.4 at one and three months of life, whereas in all other infants TBA predominated with a G/T ratio always < 1. Also, 25OHD3 and 1,25OH2D3 levels were significantly lower in preterm infants fed a taurine-free formula than in infants fed a taurine-enriched formula or human milk. Term infants fed a taurine-free formula did not show differences in the parameters studied in comparison to infants of other groups. Low taurine dietary intake appears to compromise vitamin D absorption in preterm infants, and therefore taurine supplementation of preterm infant formulas should be encouraged.
G Zamboni; G Piemonte; A Bolner; F Antoniazzi; A Dall'Agnola; H Messner; G Gambaro; L Tatò
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  82     ISSN:  0803-5253     ISO Abbreviation:  Acta Paediatr.     Publication Date:  1993 Oct 
Date Detail:
Created Date:  1993-12-23     Completed Date:  1993-12-23     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  811-5     Citation Subset:  IM    
Pediatric Endocrine Unit, University of Verona, Italy.
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MeSH Terms
Bile Acids and Salts / metabolism*
Calcifediol / blood
Calcitriol / blood
Glycocholic Acid / blood
Infant Food
Infant Nutritional Physiological Phenomena*
Infant, Newborn
Infant, Premature
Nutritive Value
Taurine / blood,  pharmacology*
Taurocholic Acid / blood
Vitamin D / metabolism*
Reg. No./Substance:
0/Bile Acids and Salts; 107-35-7/Taurine; 1406-16-2/Vitamin D; 19356-17-3/Calcifediol; 32222-06-3/Calcitriol; 475-31-0/Glycocholic Acid; 81-24-3/Taurocholic Acid

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