Document Detail

Influence of dietary habits, age and gender on plasma fatty acids levels in a population of healthy Tunisian subjects.
MedLine Citation:
PMID:  20594942     Owner:  NLM     Status:  MEDLINE    
The fatty acids composition of circulating blood lipids is expected to be altered by many factors (ageing, dietary intake, lifestyle...). In addition to the ageing consequences on their lipid status, elderly subjects represent a population at risk of nutritional imbalance. The main objective of the present study was to investigate the associations between dietary habits and the plasma fatty acids patterns in a healthy Tunisian population with an emphasis on the gender and ageing differences for the 6-desaturase activity and the EFA proportions. Nutritional habits and plasma fatty acids compositions have been therefore evaluated in 200 healthy volunteers (104 women and 96 men) aged between 40 and 82years old. The findings revealed that the 6-desaturase activity was reduced in elderly subjects (by 24% and 10% in women and men respectively). Moreover, DHA (C22:6n-3) and AA (C20:4n-6) were found to increase respectively in high fish and meat consumers. Plasma fatty acids composition could be sensitive to dietary habits according to particular food items and should then help for the establishment of optimal nutritional proportions.
Sonia Sfar; François Laporte; Hamadi Braham; Abdelhafidh Jawed; Salah Amor; Abdelhamid Kerkeni
Publication Detail:
Type:  Journal Article     Date:  2010-06-01
Journal Detail:
Title:  Experimental gerontology     Volume:  45     ISSN:  1873-6815     ISO Abbreviation:  Exp. Gerontol.     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-08-23     Completed Date:  2010-12-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0047061     Medline TA:  Exp Gerontol     Country:  England    
Other Details:
Languages:  eng     Pagination:  719-25     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Elsevier Inc. All rights reserved.
Unité de recherche, Faculté de médecine de Monastir, 5019 Monastir, Tunisia.
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MeSH Terms
Aged, 80 and over
Aging / physiology
Body Height
Body Mass Index
Body Weight
Diet Surveys
Fatty Acids / blood*
Fatty Acids, Essential / blood,  metabolism
Food Habits*
Linoleoyl-CoA Desaturase / blood
Middle Aged
Nutrition Assessment
Sex Characteristics
Reg. No./Substance:
0/Fatty Acids; 0/Fatty Acids, Essential; EC Desaturase

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