Document Detail

Influence of cycling history on the ventilatory response to cycle-ergometry in humans: a role for respiratory memory?
MedLine Citation:
PMID:  20217372     Owner:  NLM     Status:  MEDLINE    
The ventilatory (V' E) mechanisms subserving stability of alveolar and arterial PCO2 (PACO2, PaCO2) during moderate exercise (< lactate threshold, thetaL) remain controversial. As long-term modulation has been argued to be an important contributor to this control process, we proposed that subjects with no experience of cycling (NEx) might provide insight into this issue. With no exercise familiarization, 9 sedentary NEx subjects and 9 age-, sex-, and activity-matched controls (C) who had cycled regularly for recreational purposes since childhood completed a square-wave (6-min stage) cycle-ergometry test: 10 W-WR1-WR2-WR1-10 W; WR1 range 25-45 W, WR2 range 50-90 W. WRs were subsequently confirmed to <thetaL. The NEx V'E-V'CO2 slope, V'E-intercept, mean PACO2 and estimated alveolar ventilation were not different from C. In conclusion, these findings provide no support for, and possibly support for no, V'E control during moderate exercise being modulated by influences related to long-term exercise history.
Andrew J Cathcart; Brian J Whipp; Anthony P Turner; John Wilson; Susan A Ward
Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Advances in experimental medicine and biology     Volume:  669     ISSN:  0065-2598     ISO Abbreviation:  Adv. Exp. Med. Biol.     Publication Date:  2010  
Date Detail:
Created Date:  2010-03-10     Completed Date:  2010-05-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0121103     Medline TA:  Adv Exp Med Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  311-4     Citation Subset:  IM    
Centre for Exercise Science and Medicine, University of Glasgow, Glasgow, UK.
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MeSH Terms
Bicycling / physiology*
Carbon Dioxide
Exercise / physiology*
Exercise Test
Lung / physiology
Memory / physiology*
Pulmonary Ventilation / physiology*
Respiratory Dead Space / physiology
Sedentary Lifestyle
Time Factors
Reg. No./Substance:
124-38-9/Carbon Dioxide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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