Document Detail


Influence of cisapride on food-stimulated gastro-oesophageal reflux: a radiological study.
MedLine Citation:
PMID:  2204995     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The influence of Cisapride on food-stimulated gastro-oesophageal reflux mechanisms was studied in a double-blind cross-over investigation in 24 consecutive patients selected by endoscopy, 12 with microscopical evidence of gastro-oesophageal reflux and 12 with additional macroscopic oesophagitis. 63% had food-stimulated gastro-oesophageal reflux, and Cisapride significantly reduced the tendency to gastro-oesophageal reflux and mucosal contact time between gastric content and the oesophageal mucosa in 73% of these patients. It is concluded that Cisapride could be valuable in the treatment of gastro-oesophageal reflux.
Authors:
J Gelineck; K Aksglade; P Funch-Jensen; P Thommesen
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Röntgen-Blätter; Zeitschrift für Röntgen-Technik und medizinisch-wissenschaftliche Photographie     Volume:  43     ISSN:  0300-8592     ISO Abbreviation:  Rontgenblatter     Publication Date:  1990 Aug 
Date Detail:
Created Date:  1990-10-17     Completed Date:  1990-10-17     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0413560     Medline TA:  Rontgenblatter     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  352-4     Citation Subset:  IM    
Affiliation:
Department of Radiology and Gastroenterology, Aarhus Kommunehospital, University of Aarhus.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Barium Sulfate / diagnostic use
Cisapride
Clinical Trials as Topic
Double-Blind Method
Esophagitis, Peptic / drug therapy*,  radiography
Female
Gastroesophageal Reflux / drug therapy*,  radiography
Humans
Male
Middle Aged
Piperidines / therapeutic use*
Serotonin Antagonists*
Chemical
Reg. No./Substance:
0/Piperidines; 0/Serotonin Antagonists; 7727-43-7/Barium Sulfate; 81098-60-4/Cisapride

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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