Document Detail

Influence of chronic caprine arthritis-encephalitis virus infection on the population of peripheral blood leukocytes.
MedLine Citation:
PMID:  22439329     Owner:  NLM     Status:  In-Process    
The influence of caprine arthritis-encephalitis (CAE) virus infection on the population of peripheral blood leukocytes in goats was evaluated. For this purpose two groups of adult dairy female goats were formed. The experimental group consisted of 17 goats, which had been naturally infected for many years. The control group comprised 29 non-infected goats, which originated from CAE-free herd. All goats were clinically healthy. Whole blood was collected and tested in hematological analyzer and light microscope to assess the total number of leukocytes and the percentage of four leukocyte populations--neutrophils, eosinophils, monocytes and lymphocytes. Then, flow cytometry with monoclonal antibodies against several surface antigens (namely CD14, CD2, B-B2, CD4, CD8h, TCR-N6, WC1-N2 and WC1-N3) was performed to assess the proportion of lymphocyte subpopulations. Statistically significant differences (alpha < or = 0.01) were observed only in the subpopulations of T lymphocytes--percentage of all subpopulations were significantly higher in the group of seropositive goats. No statistically significant differences were revealed with respect to the total number of blood leukocytes, the average percentage of blood leukocyte populations and proportions of both T and B lymphocytes.
J Kaba; A Winnicka; M Zaleska; M Nowicki; E Bagnicka
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Polish journal of veterinary sciences     Volume:  14     ISSN:  1505-1773     ISO Abbreviation:  Pol J Vet Sci     Publication Date:  2011  
Date Detail:
Created Date:  2012-03-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101125473     Medline TA:  Pol J Vet Sci     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  585-90     Citation Subset:  IM    
Division of Infectious Diseases and Epidemiology, Faculty of Veterinary Medicine, Warsaw University of Life Sciences, Nowoursynowska 159c, 02-776 Warsaw, Poland.
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