Document Detail

Influence of cerebrolysin(r) on the resistance of rats to anoxia.
MedLine Citation:
PMID:  135987     Owner:  NLM     Status:  MEDLINE    
Single injections of Cerebrolysin(R) did not affect the resistance of rats to anoxia, irrespective of age. Cerebrolysin(R) significantly raised the resistance of the young of females injected ten times i.p. with the same dose during pregnancy. The repeated (5-fold) administration of Cerebrolysin(R) significantly raised the resistance of 35-day-old rats to anoxia and, in high concentrations, it also increased the resistance of adult rats. The effect of Cerebrolysin(R) is correlated to the proportion of amino acids, aligopeptides and the nucleotides they contain. The mere administration of a mixture of amino acids or of some other hydrolysate (Testolysin) was ineffective in this respect.
M Trojanová; F Karásek; V Pruzková; J Mourek
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Physiologia Bohemoslovaca     Volume:  25     ISSN:  0369-9463     ISO Abbreviation:  Physiol Bohemoslov     Publication Date:  1976  
Date Detail:
Created Date:  1977-01-03     Completed Date:  1977-01-03     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0175317     Medline TA:  Physiol Bohemoslov     Country:  CZECHOSLOVAKIA    
Other Details:
Languages:  eng     Pagination:  319-23     Citation Subset:  IM    
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MeSH Terms
Amino Acids / therapeutic use*
Anoxia / prevention & control*
Tissue Extracts / administration & dosage,  therapeutic use
Reg. No./Substance:
0/Amino Acids; 0/Tissue Extracts

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