Document Detail

Influence of cardiac output on the correlation between mixed venous and central venous oxygen saturation.
MedLine Citation:
PMID:  1419454     Owner:  NLM     Status:  MEDLINE    
The influence of cardiac output on the correlation between central venous oxygen saturation and mixed venous oxygen saturation was assessed in 51 patients who had both a pulmonary artery catheter and separate central venous catheter in situ. Seventy-six paired samples were taken from the catheters and oxygen saturation measured immediately in a Ciba Corning 2500 Co-oximeter. Cardiac output was measured using a standard thermodilution technique. The data were separated into groups with low cardiac index (< 2.5 litre min-1 m-2; n = 20), medium cardiac index (2.5-4.0 litre min-1 m-2; n = 36) and high cardiac index (> 4.0 litre min-1 m-2; n = 20). The correlation coefficients of the three groups were: low cardiac index 0.95, medium cardiac index 0.88 and high cardiac index 0.95 (P < .001 for all three groups). All measurements were made before any x-ray and necessary repositioning of the central venous catheter. These results suggest that central venous oxygen saturation is a useful estimate of mixed venous oxygen saturation and that the influence of cardiac output on that estimate is minimal.
J C Berridge
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British journal of anaesthesia     Volume:  69     ISSN:  0007-0912     ISO Abbreviation:  Br J Anaesth     Publication Date:  1992 Oct 
Date Detail:
Created Date:  1992-12-21     Completed Date:  1992-12-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372541     Medline TA:  Br J Anaesth     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  409-10     Citation Subset:  IM    
Academic Unit of Anaesthesia, University of Leeds.
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MeSH Terms
Blood Specimen Collection / methods*
Cardiac Output / physiology*
Catheterization, Central Venous
Heart Catheterization
Middle Aged
Oxygen / blood*
Reg. No./Substance:
Comment In:
Br J Anaesth. 1993 May;70(5):595   [PMID:  8318340 ]

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