Document Detail

Influence of bolus consistency and position on esophageal high-resolution manometry findings.
MedLine Citation:
PMID:  17932767     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Conventional esophageal manometry evaluating liquid swallows in the recumbent position measures pressure changes at a limited number of sites and does not assess motility during solid swallows in the physiologic upright position. AIM: To evaluate esophageal motility abnormalities during water and bread swallows in the upright and recumbent positions using high-resolution manometry (HRM). METHODS: Thirty-two-channel HRM testing was performed using water (10 ml each) and bread swallows in the upright and recumbent positions. The swallows were considered normal if the distal peristaltic segment >30 mmHg was >5 cm, ineffective if the 30-mmHg pressure band was <5 cm, and simultaneous if the onset velocity of the 30 mmHg pressure band was >8 cm/s. Abnormal esophageal manometry was defined as the presence of > or =30% ineffective and/or > or =20% simultaneous contractions. RESULTS: The data from 96 patients (48 F; mean age 51 years, range 17-79) evaluated for dysphagia (56%), chest pain (22%), and gastroesophageal reflux disease (GERD) symptoms (22%) were reviewed. During recumbent water swallows, patients with dysphagia, chest pain, and GERD had a similar prevalence of motility abnormalities. During upright bread swallows, motility abnormalities were more frequent (p = 0.01) in patients with chest pain (71%) and GERD (67%) compared to patients with dysphagia (37%). CONCLUSIONS: Evaluating bread swallows in the upright position reveals differences in motility abnormalities overlooked by liquid swallows alone.
Anita Bernhard; Daniel Pohl; Michael Fried; Donald O Castell; Radu Tutuian
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Publication Detail:
Type:  Journal Article     Date:  2007-10-12
Journal Detail:
Title:  Digestive diseases and sciences     Volume:  53     ISSN:  0163-2116     ISO Abbreviation:  Dig. Dis. Sci.     Publication Date:  2008 May 
Date Detail:
Created Date:  2008-04-10     Completed Date:  2008-06-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7902782     Medline TA:  Dig Dis Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1198-205     Citation Subset:  AIM; IM    
Division of Gastroenterology and Hepatology, University Hospital of Zurich, Zurich, Switzerland.
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MeSH Terms
Analysis of Variance
Chest Pain
Chi-Square Distribution
Deglutition Disorders / physiopathology*
Esophageal Motility Disorders / physiopathology*
Gastroesophageal Reflux / physiopathology*
Manometry / methods*
Middle Aged
Retrospective Studies
Statistics, Nonparametric
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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