| Influence of blood storage after in vitro exposure on the yield of micronuclei observed in human lymphocytes. | |
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MedLine Citation:
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PMID: 8488462 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In a cooperative study, four laboratories evaluated the micronucleus test in irradiated and non-irradiated lymphocytes with respect to time of storage, the difference between X-ray and gamma exposure and inter-observer variance. The results were compared with parallel studies on dicentric aberrations. No significant differences between laboratories, with respect to storage time or between gamma and X-irradiation were observed for micronuclei and dicentrics using analysis of variance. However, micronuclei are not suitable for an assessment of exposure inhomogeneity because of a significant overdispersion already in controls and homogeneously irradiated samples. |
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Authors:
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I Lopez; A Hilali; L Verschaeve; C Laurent; C Bugueno; E D Léonard; A Maes; P Jadot; G Goens; S Sanhueza |
Publication Detail:
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Type: Comparative Study; In Vitro; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al] Volume: 169 ISSN: 0179-7158 ISO Abbreviation: Strahlenther Onkol Publication Date: 1993 Apr |
Date Detail:
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Created Date: 1993-06-07 Completed Date: 1993-06-07 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8603469 Medline TA: Strahlenther Onkol Country: GERMANY |
Other Details:
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Languages: eng Pagination: 258-62 Citation Subset: IM |
Affiliation:
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Laboratorio Dosimetria Biologica, CEN La Reina, Santiago, Chile. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Belgium Blood Preservation* / statistics & numerical data Chile Dose-Response Relationship, Radiation Humans Lymphocytes / radiation effects*, ultrastructure Male Micronuclei, Chromosome-Defective / radiation effects* Micronucleus Tests / statistics & numerical data Observer Variation Time Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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