Document Detail

Influence of the base on the results of clinical trials with topical corticosteroids.
MedLine Citation:
PMID:  372027     Owner:  NLM     Status:  MEDLINE    
A comparative trial between betamethasone valerate and halcinonide has shown the former to be superior, thus contradicting the results from other trials. It is thought that the discrepancy is due to differences in the nature of the preparations used in the various studies. It is suggested that note is made of the base used in trials before final conclusions about the efficicacy of steroids are made.
D I Vollum; C G Sparkes
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Dermatologica     Volume:  158     ISSN:  0011-9075     ISO Abbreviation:  Dermatologica     Publication Date:  1979  
Date Detail:
Created Date:  1979-06-26     Completed Date:  1979-06-26     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0211607     Medline TA:  Dermatologica     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  293-8     Citation Subset:  IM    
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MeSH Terms
Administration, Topical
Betamethasone / administration & dosage*,  adverse effects,  analogs & derivatives*,  therapeutic use
Betamethasone 17-Valerate / administration & dosage*,  adverse effects,  therapeutic use
Clinical Trials as Topic
Double-Blind Method
Drug Evaluation
Eczema / drug therapy
Halcinonide / administration & dosage,  therapeutic use
Psoriasis / drug therapy
Skin Diseases / drug therapy*
Reg. No./Substance:
0/Ointments; 2152-44-5/Betamethasone 17-Valerate; 3093-35-4/Halcinonide; 378-44-9/Betamethasone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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