Document Detail

Influence of anaesthetic agents on the survival of rats following acute ischaemia of the bowel.
MedLine Citation:
PMID:  518793     Owner:  NLM     Status:  MEDLINE    
We compared the effects of ketamine and halothane anaesthesia on the survival of rats subjected to superior mesenteric artery occlusion. Survival was significantly greater with halothane. Animals anaesthetized with ketamine developed arterial hypocarbia during bowel ischaemic shock, while those receiving halothane did not. Arterial hypoxaemia was not present in either group. Haematocrits increased in both groups following bowel ischaemia. Excess lactate was increased significantly in non-survivors compared with survivors. The survival data contrast with previous results obtained after haemorrhagic hypotension and emphasize the need to consider differing therapeutic approaches in the various shock states.
P H Bavister; D E Longnecker
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  British journal of anaesthesia     Volume:  51     ISSN:  0007-0912     ISO Abbreviation:  Br J Anaesth     Publication Date:  1979 Oct 
Date Detail:
Created Date:  1980-03-17     Completed Date:  1980-03-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372541     Medline TA:  Br J Anaesth     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  921-5     Citation Subset:  IM    
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MeSH Terms
Anesthesia, Inhalation*
Anesthesia, Intravenous*
Blood Pressure
Carbon Dioxide / blood
Intestines / blood supply
Ischemia / complications,  etiology
Lactates / blood
Mesenteric Arteries
Mesenteric Vascular Occlusion / complications*
Partial Pressure
Shock / etiology,  mortality*
Reg. No./Substance:
0/Lactates; 124-38-9/Carbon Dioxide; 151-67-7/Halothane; 6740-88-1/Ketamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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