| Influence of aluminium on neurotoxicity of lead in adult male albino rats. | |
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MedLine Citation:
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PMID: 15266904 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Influence of aluminium on neurotoxicity of lead was studied in male albino rats. Aluminium enhanced the net deposition of lead in brain. This was further substantiated by higher levels of malondialdehyde (MDA), and lower activities of acetylcholinesterase enzyme in the brain homogenates of the rats treated with both lead and aluminium as compared to those of rats treated with lead only. In lead plus aluminium treated animals, a significant neurological deficit was observed when the animals were subjected to rota-rod, traction performance (TP) and tail immersion tests. |
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Authors:
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A Shakoor; P K Gupta; M Kataria |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Indian journal of experimental biology Volume: 41 ISSN: 0019-5189 ISO Abbreviation: Indian J. Exp. Biol. Publication Date: 2003 Jun |
Date Detail:
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Created Date: 2004-07-22 Completed Date: 2004-08-19 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0233411 Medline TA: Indian J Exp Biol Country: India |
Other Details:
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Languages: eng Pagination: 587-91 Citation Subset: IM |
Affiliation:
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Division of Pharmacology and Toxicology, Indian Veterinary Research Institute, Izatnagar 243 122, India. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acetylcholinesterase
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metabolism Aluminum / toxicity* Animals Brain Stem / drug effects*, enzymology Male Malondialdehyde / metabolism Rats Reaction Time |
| Chemical | |
Reg. No./Substance:
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542-78-9/Malondialdehyde; 7429-90-5/Aluminum; EC 3.1.1.7/Acetylcholinesterase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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