Document Detail

Influence of alcohol on several physiological functions and its reversibility: a surgical view.
MedLine Citation:
PMID:  1471555     Owner:  NLM     Status:  MEDLINE    
Alcohol intake influences several physiological functions, including the haemostatic system, the cellular immune defence and the cardiac function, but to a different degree depending on the drinking habits. Restoration of these functions after withdrawal seems time related. The haemostatic imbalance normalizes within two or three weeks of soberness while the immune system requires about two months to recover. Recent studies have showed very increased postoperative morbidity after surgery in alcohol abusers, which may be explained by alcohol-induced physiological dysfunctions. Theoretically, two months of abstinence before a surgical procedure would diminish the increased postoperative morbidity among alcohol abusers. However, further investigation is necessary to establish a clinical effect of preoperative withdrawal from alcohol.
H Tønnesen
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Acta psychiatrica Scandinavica. Supplementum     Volume:  369     ISSN:  0065-1591     ISO Abbreviation:  Acta Psychiatr Scand Suppl     Publication Date:  1992  
Date Detail:
Created Date:  1993-01-25     Completed Date:  1993-01-25     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0370365     Medline TA:  Acta Psychiatr Scand Suppl     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  67-71     Citation Subset:  IM    
Alcohol Research Center, Copenhagen.
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MeSH Terms
Alcoholism / immunology,  physiopathology*
Heart Rate / physiology
Homeostasis / physiology
Postoperative Complications*
Stress, Physiological

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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