| Influence of acetaminophen consumption on perceived exertion at the lactate concentration threshold. | |
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MedLine Citation:
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PMID: 16491671 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The purpose of this investigation was to study effects of acetaminophen consumption on ratings of perceived exertion and estimated time limit responses at the lactate threshold. 98 young regional to national level athletes performed a graded exhausting exercise on an outdoor running track to estimate their maximal aerobic velocity and the velocity associated with their lactate concentration threshold. Urine (30 mL) was collected during this test and analysed for numerous substances. During urinary screening for doping substances, 9 acetaminophen consumers (9.2%) among the 98 included athletes were detected. These acetaminophen consumers have significantly lower perceived exertion at velocity corresponding to the lactate concentration threshold than nonconsumers (11.9 +/- 2.1 vs 13.6 +/- 2.1, respectively) although they were at the same relative exercise intensity. This result shows that acetaminophen consumption may have mediated the perceived exertion response at the lactate concentration threshold. This may then suggest that the pain induced by training load could be a factor in use of self-prescribed pain relievers. Such consumption must be taken into account by medical staff, trainers, or educators who have to give information on the use and adverse effects of this substance and to propose palliative methods to their athletes. |
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Authors:
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M Garcin; L Mille-Hamard; V Billat; L Humbert; M Lhermitte |
Publication Detail:
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Type: Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Perceptual and motor skills Volume: 101 ISSN: 0031-5125 ISO Abbreviation: Percept Mot Skills Publication Date: 2005 Dec |
Date Detail:
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Created Date: 2006-02-22 Completed Date: 2006-05-24 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0401131 Medline TA: Percept Mot Skills Country: United States |
Other Details:
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Languages: eng Pagination: 675-83 Citation Subset: IM |
Affiliation:
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Laboratoire d'Etudes de la Motricité Humaine EA 3608, Faculté des Sciences du Sport et de l'Education Physique, Université de Lille 2, 9 rue de l'Université, 59790 Ronchin, France. murielle.garcin@univ-lille2.fr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acetaminophen
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pharmacokinetics,
pharmacology* Adolescent Adult Anaerobic Threshold / drug effects* Analgesics, Non-Narcotic / pharmacokinetics, pharmacology* Exercise / psychology* Female Humans Lactic Acid / blood* Male Physical Endurance / drug effects Physical Exertion / drug effects* Physical Fitness Running / psychology Set (Psychology)* Substance Abuse Detection |
| Chemical | |
Reg. No./Substance:
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0/Analgesics, Non-Narcotic; 103-90-2/Acetaminophen; 50-21-5/Lactic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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