| Influence of Zinc Deficiency to the Mice Infected with Babesia microti. | |
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MedLine Citation:
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PMID: 20953135 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Zinc (Zn) is an essential trace element for DNA synthesis and for cell growth and differentiation. The deficiency induces a wide range of disorders including immunodeficiency. In this study, the influence of Zn deficiency to the mice infected with Babesia microti was examined, and was compared with the influence in the rats infected with B. rodhaini previously reported. Experiments of B. microti infection were conducted using Zn-deficient (ZD; allowed to eat ad libitum on the ZD diet), Zn-adequate (ZA; allowed to eat ad libitum on the ZA diet), and diet-restricted (DR; supplied 2 g/day on the ZA diet) mice. It was suggested that the Zn deficiency exacerbated the infection dynamics of the mice with B. microti by the growth retardation, the reduction of immunity and the decrease in PCV. The results in the mice supported the consequences in the rats previously reported. |
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Authors:
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Keiko Hamaguchi; Kazunori Ike; Yuko Yamazaki; Tatsushi Morita; Soichi Imai |
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Publication Detail:
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Type: Journal Article Date: 2010-10-12 |
Journal Detail:
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Title: The Journal of veterinary medical science / the Japanese Society of Veterinary Science Volume: 73 ISSN: 0916-7250 ISO Abbreviation: J. Vet. Med. Sci. Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-03-07 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9105360 Medline TA: J Vet Med Sci Country: Japan |
Other Details:
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Languages: eng Pagination: 263-7 Citation Subset: IM |
Affiliation:
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Laboratory of Veterinary Parasitology, Department of Veterinary Medicine, Faculty of Veterinary Science, Nippon Veterinary and Life Science University. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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