Document Detail

Influence of Threatened Miscarriage on Pregnancy and Early Postpartum Period: A Case-Control Report.
MedLine Citation:
PMID:  25053196     Owner:  NLM     Status:  Publisher    
Abstract Objective: To evaluate the influence of threatened miscarriage on obstetric complications during pregnancy and early postpartum period. Methods: In this case-control study, hospital records of 12,050 first-trimester patients between January 2011 and December 2012 at the Research and Educational Hospital in Ankara, Turkey, were used. Of the 12,050 patients, 481 threatened miscarriage patients were evaluated. The control group was formed by age- and body mass index (BMI)-matched cases without first trimester bleeding. Abortion, intrauterine foetal demise, preterm birth, preeclampsia, antenatal haematoma, uterine atony placental abruption, and low birth-weights were compared between the study and the control group. Results: When compared with the control group, the risk of having a preterm birth (p=0.014 OR, 1.95; 95% CI, 1.15-3.24), low-birth-weight infant (p=0.001 OR, 2.33; %95CI, 1.45-3.83), and abortion (p=0.00 OR, 2.55; 95% CI, 1.62-3.91) increased in cases of threatened miscarriage. However, the risk of uterine atony was decreased (p=0.006 OR, 0.09; 95% CI, 0.12-0.7) in the threatened miscarriage group when compared with the control group. Threatened miscarriage did not increase the risk of placenta praevia, placental abruption, or intrauterine foetal demise. Conclusion: Increased complications after threatened miscarriage is probably due to the persistence of a triggering mechanism. As preterm birth and abortion rate increased, whilst uterine atony rate decreased, one of the mechanisms causing threatened miscarriage might be increased uterine contractility.
Safak Ozdemici; Ertugrul Karahanoglu; Deniz Esinler; Orhan Gelisen; Fulya Kayikcioglu
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-7-23
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  -     ISSN:  1476-4954     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2014 Jul 
Date Detail:
Created Date:  2014-7-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1-13     Citation Subset:  -    
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