Document Detail

Influence of Smoking and Alcohol during Pregnancy on Outcome of VLBW Infants.
MedLine Citation:
PMID:  24363249     Owner:  NLM     Status:  Publisher    
Nicotine and alcohol consumption have been associated with premature delivery and adverse neonatal outcome. We wanted to analyze the influence of self-reported nicotine and alcohol consumption on outcome of VLBW infants.In an ongoing multicenter study 2 475 parents of former very low birth weight (VLBW) infants born between January 2009 and December 2011 answered questionnaires about maternal smoking habits and alcohol consumption during pregnancy. 2 463 (99.5%) completed questions on alcohol consumption and 2 462 (99.5%) on smoking habits. These infants were stratified to reported maternal smoking and alcohol consumption during pregnancy. We compared the reasons for premature delivery, neonatal outcome and parental reports on bronchitis during the first year of life, as well as growth and development at age 2 years to pregnancy exposure.In nicotine exposed infants intrauterine growth restriction (31 vs. 21%, p<0.01), a birth weight below the 10th percentile (26 vs. 17%, p<0.01) and placenta abruption (9.2 vs. 5.8%, p<0.05) was seen more often. Premature rupture of membranes (24 vs. 30%, p<0.05) or HELLP syndrome (6 vs. 11%, p<0.01) was less frequent. A birth weight below the 3rd percentile was seen more frequently in mothers with reported alcohol consumption (13 vs. 6%, p<0.05). We noted an increased rate of BPD and ROP if mothers reported smoking during pregnancy (p<0.05). Growth parameters and scores on Bayley Sscales of infant development at age 2 years did not differ.Smoking during pregnancy results in a high rate of growth restricted VLBW infants. Prenatal exposition to nicotine seems to increase postnatal complications such as BPD und ROP.
J Spiegler; R Jensen; H Segerer; S Ehlers; T Kühn; A Jenke; C Gebauer; J Möller; T Orlikowsky; F Heitmann; K Boeckenholt; E Herting; W Göpel
Related Documents :
8684739 - Sonographic prediction of shoulder dystocia in infants of diabetic mothers.
3578189 - Antireflux surgery in infants with bronchopulmonary dysplasia.
15937699 - Lung volumes in infants who had mild to moderate bronchopulmonary dysplasia.
2030919 - Sleep apnea and hypoxemia in recently weaned premature infants with and without broncho...
8604659 - Use of the intramuscular relative-dose-response test to predict bronchopulmonary dyspla...
8414739 - Dexamethasone treatment suppresses collagen synthesis in infants with bronchopulmonary ...
12907229 - Development as a dynamic system.
22173519 - A decrease in the number of cases of necrotizing enterocolitis associated with the enha...
20220759 - Iron supplementation for preterm infants receiving restrictive red blood cell transfusi...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-12-20
Journal Detail:
Title:  Zeitschrift fur Geburtshilfe und Neonatologie     Volume:  217     ISSN:  1439-1651     ISO Abbreviation:  Z Geburtshilfe Neonatol     Publication Date:  2013 Dec 
Date Detail:
Created Date:  2013-12-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9508901     Medline TA:  Z Geburtshilfe Neonatol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  215-219     Citation Subset:  -    
Copyright Information:
© Georg Thieme Verlag KG Stuttgart · New York.
Vernacular Title:
Einfluss von Rauchen und Alkoholkonsum während der Schwangerschaft auf das Outcome von Frühgeborenen unter 1500 Gramm.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Review on Current Management and Outcome Data of Echogenic Lung Lesions and Hydrothorax of the Fetus...
Next Document:  Thapsigargin affects presenilin-2 but not presenilin-1 regulation in SK-N-BE cells.