Document Detail


Influence of protein- versus carbohydrate-enriched feedings on physiological responses during an ultraendurance climbing race.
MedLine Citation:
PMID:  19821225     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study investigated effects of a high protein (PROT) versus a high carbohydrate (CHO) diet on performance and physiological responses during an ultraendurance climbing race at moderate altitude. On two different periods, in a randomised crossover design, ten climbers (30.0+/-0.9 years) participated in the race (duration 29 h approximately, energy expenditure 43.6+/-1.2 MJ.day (-1)) and were fed either with the PROT (30% protein content) or the CHO diet (68% carbohydrate) each providing 16.74 MJ. Mental performance was assessed by the Stroop test and we estimated maximal voluntary strength of quadriceps muscle. We quantified metabolic and hormonal circulating concentrations. Mental performance was unaffected after the two races, while muscular performance and body weight were decreased (both p<0.01) with no diet effects. Decreases were measured for IGF-I concentration and its binding protein IGFBP-3 (p<0.001), and increases for cortisol and norepinephrine (p<0.01) with no diet effects. Glucose concentration decreased (p<0.05) without diet effects, while amino acids (leucine, isoleucine, valine, and tyrosine) decreased in CHO group (p<0.001). Leptin concentration decreased (p<0.001) without diet effects, whereas total ghrelin increased in CHO group (p<0.01). Our results showed that a high PROT or high CHO intake during physical exertion at moderate altitude maintained mental performance, but did not limit muscle force reduction and body weight loss. There was decreased glucose availability, and hormonal responses indicated both catabolism and extreme energy deficiency induced by exercise with opposite responses of ghrelin and leptin. The ghrelin response was additionally indicative of macronutrient intake during the race.
Authors:
C Bourrilhon; R Lepers; M Philippe; P Van Beers; M Chennaoui; C Drogou; M C Beauvieux; P Burnat; C Y Guezennec; D Gomez-Merino
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2009-10-09
Journal Detail:
Title:  Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et m?tabolisme     Volume:  42     ISSN:  1439-4286     ISO Abbreviation:  Horm. Metab. Res.     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2009-12-24     Completed Date:  2010-03-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0177722     Medline TA:  Horm Metab Res     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  31-7     Citation Subset:  IM    
Copyright Information:
Georg Thieme Verlag KG Stuttgart New York.
Affiliation:
Department of Physiology, IMASSA, 91223 Br?tigny-sur-Orge, France. cbourrilhon@imassa.fr
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MeSH Terms
Descriptor/Qualifier:
Adult
Altitude
Dietary Carbohydrates / administration & dosage,  metabolism*
Dietary Proteins / administration & dosage,  blood,  metabolism*
Energy Metabolism
Humans
Insulin / blood
Insulin-Like Growth Factor Binding Protein 3 / blood
Insulin-Like Growth Factor I / metabolism
Male
Mountaineering / physiology*
Physical Endurance*
Chemical
Reg. No./Substance:
0/Dietary Carbohydrates; 0/Dietary Proteins; 0/Insulin-Like Growth Factor Binding Protein 3; 11061-68-0/Insulin; 67763-96-6/Insulin-Like Growth Factor I

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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