| Influence of pregnancy on Trypanosoma cruzi parasitemia in chronically infected women in a rural Bolivian community. | |
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MedLine Citation:
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PMID: 21540394 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To determine the role of pregnancy on Trypanosoma cruzi parasitemia, a matched cohort study was carried out in a rural Bolivian community comparing parasite rates in gravidae, puerperae, and non-pregnant infected women. A selection of 67 chronically infected women, who delivered between March 2004 and May 2005, were initially evaluated during the third trimester of pregnancy and again after delivery. They were matched for age, parity, and location with 104 seropositive non-pregnant women, who likewise had submitted blood for microscopic examination for T. cruzi parasites in June 2005. Seroreactive pregnant women had a higher rate of T. cruzi parasitemia (14.9%) than matched non-pregnant infected women (2.9%; P = 0.004). After delivery, parasitemia significantly decreased during puerperium (1.5%) compared with the period of pregnancy (14.9%; P = 0.03). This study showed an increase of parasite loads in maternal peripheral blood, during the third trimester, and a significant decline after delivery. |
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Authors:
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Laurent Brutus; Jean-Christophe Ernould; Jorge Postigo; Mario Romero; Dominique Schneider; José-Antonio Santalla |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The American journal of tropical medicine and hygiene Volume: 84 ISSN: 1476-1645 ISO Abbreviation: Am. J. Trop. Med. Hyg. Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-05-04 Completed Date: 2011-07-01 Revised Date: 2012-05-08 |
Medline Journal Info:
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Nlm Unique ID: 0370507 Medline TA: Am J Trop Med Hyg Country: United States |
Other Details:
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Languages: eng Pagination: 808-12 Citation Subset: AIM; IM |
Affiliation:
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UMR216--Mother and Child Facing Tropical Diseases, Institut de Recherche pour le Développement/Université Paris Descartes, 4 avenue de l’Observatoire, Paris, France. laurent.brutus@ird.fr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Bolivia Female Humans Middle Aged Parasitemia / complications* Pregnancy Pregnancy Complications, Parasitic / blood* Rural Population* Trypanosoma cruzi / isolation & purification* Trypanosomiasis / complications*, parasitology |
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