Document Detail


Influence of Perinatal Factors in Short- and Long-Term Outcomes of Infants Born at 23 Weeks of Gestation.
MedLine Citation:
PMID:  25486287     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Objective Investigate the influence of perinatal factors on short- and long-term outcomes for infants born at 23 weeks of gestation. Study Design This is a retrospective study over a 25-year period (1987-2011) of 87 successfully resuscitated infants at 23 weeks of gestation. We investigated the effects of poor prenatal care, race, gender, chorioamnionitis, antenatal corticosteroids, delivery route/location, low 5-minute Apgar score, birth weight, and multiple births on short- and long-term outcomes. Results The mortality rate was 43% (37/87). A total of 88% (44/50) of the survivors were followed at 2 years corrected age with 66% (29/44) diagnosed with a moderate-to-severe neurological impairment. Outborn and multiple birth infants had significantly higher mortality (p-value 0.042 and 0.006, respectively). Lack of exposure to antenatal steroids and lower birth weight significantly increased the disability score (p-value 0.042 and 0.003, respectively). Conclusion Multiple perinatal factors significantly influence outcomes at the threshold of viability.
Authors:
Hamzah R Miltaha; Lisa M Fahey; Christine H Sajous; John C Morrison; Jonathan K Muraskas
Related Documents :
25349867 - The effect of the educational program on iranian premature infants' parental stress in ...
22984637 - Longitudinal developmental profile of children from low socio-economic circumstances in...
21126207 - Non-infectious conditions and gestational age influence c-reactive protein values in ne...
25396027 - Maternal mortality in central province, kenya, 2009-2010.
25345527 - Can the perinatal information system in peru be used to measure the proportion of adver...
23950567 - Growth of very low birth weight infants after increased amino acid and protein administ...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-12-8
Journal Detail:
Title:  American journal of perinatology     Volume:  -     ISSN:  1098-8785     ISO Abbreviation:  Am J Perinatol     Publication Date:  2014 Dec 
Date Detail:
Created Date:  2014-12-8     Completed Date:  -     Revised Date:  2014-12-9    
Medline Journal Info:
Nlm Unique ID:  8405212     Medline TA:  Am J Perinatol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Necrotizing Enterocolitis in Infants with Ductal-Dependent Congenital Heart Disease.
Next Document:  Risk Factors and Outcomes of Late-Onset Bacterial Sepsis in Preterm Neonates Born at?<?32 Weeks' Ges...