| Influence of NaCl supplementation on vasopressin secretion and water excretion in premature infants. | |
| | |
MedLine Citation:
|
PMID: 8260554 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The study was carried out to assess the possible involvement of excess AVP and free water retention in the development of late hyponatremia by comparing the postnatal course of plasma AVP and urinary excretion of AVP and sodium as well as creatinine, osmolar and free water clearances in premature infants with (group S) and without (group NS) NaCl supplementation. Plasma total protein and albumin concentrations were also determined. Group NS consisted of 8 infants with a birth weight of 1,150-1,730 g (mean: 1,440 g) and gestational age of 28-32 weeks (mean: 30.4 weeks). Group S included 8 infants with a mean birth weight of 1,390 g (range: 980-1,700 g) and a mean gestational age of 30.1 weeks (range: 27-32 weeks). Measurements were made on the 7th day and weekly thereafter until the 5th week of life. NaCl supplementation was given in a dose of 3-5 and 1.5-2.5 mmol/kg/day for 8-21 and 22-35 days, respectively. Infants receiving sodium supplements had significantly greater urinary sodium excretion (p < 0.01), retained more sodium (p < 0.01), maintained plasma sodium at normal levels and gained weight at slightly higher rates when compared with those on low sodium. Plasma AVP tended to be higher in group S but did not differ significantly from that in NS group. Urinary AVP excretion, however, either expressed in ng/day or ng/100 ml GFR, was significantly higher in group S, although the age-related increase could not be seen when correction was made for GFR.(ABSTRACT TRUNCATED AT 250 WORDS) |
| | |
Authors:
|
E Sulyok; W Rascher; Z Baranyai; T Ertl; L Kerekes |
Related Documents
:
|
7222324 - The myth of the clean catch urine specimen. 8695994 - Generation of hydroxytrimethyllysine from trimethyllysine limits the carnitine biosynth... 8969934 - Activity of the adrenal fetal zone in preterm infants continues to term. 11484904 - Role of metabolism in arsenic toxicity. 3515304 - Neonatal intracranial hemorrhage and phenobarbital. 2506874 - Fatty acid patterns in parenterally fed premature and term infants: changes induced by ... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Biology of the neonate Volume: 64 ISSN: 0006-3126 ISO Abbreviation: Biol. Neonate Publication Date: 1993 |
Date Detail:
|
Created Date: 1994-01-25 Completed Date: 1994-01-25 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0247551 Medline TA: Biol Neonate Country: SWITZERLAND |
Other Details:
|
Languages: eng Pagination: 201-8 Citation Subset: IM |
Affiliation:
|
County Children's Hospital, Pécs, Hungary. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Arginine Vasopressin
/
blood*,
urine* Blood Proteins / metabolism Creatinine / urine Diuresis / drug effects* Gestational Age Glomerular Filtration Rate Humans Infant Infant, Newborn Infant, Premature / physiology* Natriuresis Serum Albumin / metabolism Sodium Chloride / administration & dosage, therapeutic use* |
| Chemical | |
Reg. No./Substance:
|
0/Blood Proteins; 0/Serum Albumin; 113-79-1/Arginine Vasopressin; 60-27-5/Creatinine; 7647-14-5/Sodium Chloride |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Cerebral hemodynamics and oxygenation in preterm infants after low-vs. high-dose surfactant replacem...
Next Document: Changes in static and dynamic skin fold measurements in the first 60 hours of life: higher values fo...