Document Detail


Influence of Aortic Dimensions on the Hemodynamic Performance of Small Aortic Valve Prostheses: Impact on Patient/Prosthesis Mismatch.
MedLine Citation:
PMID:  21544789     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: Since Doppler echocardiography takes no account of pressure recovery, the true hemodynamic burden of aortic valve prostheses remains vague. The purpose of this study was to elucidate the methodological error of Doppler gradient estimation by means of a model demonstrating the different influence of aortic root diameters on net and Doppler gradients, respectively. This matters especially in small valves and the related patient/prosthesis mismatch calculation. METHODS: Two bileaflet small aortic valve prostheses (19 mm SJM Regent® and On-X® valve) were tested using a pulsatile circulatory mock loop simulator with two different aortic models: one with statistically normal diameters according to annular size, another one simulating an aortic aneurysm of 50 mm. Doppler and simultaneously recorded net gradients as well as systolic energy losses were obtained for different hemodynamic conditions. RESULTS: In all measurements a significant amount of pressure recovery was observed. In cases of aortic aneurysm systolic energy loss increased significantly for each cardiac output at each heart rate ( P < 0.0028), reflected by a significant ( P < 0.0001) increase in net gradients. The corresponding Doppler gradients were unchanged. This indicates significantly less pressure recovery ( P < 0.0001) in the aneurysmatic aorta. CONCLUSIONS: Geometry of the ascending aorta considerably alters aortic valve hemodynamic parameters. The hemodynamic function of small aortic valve prostheses, especially with corresponding normal outflow dimensions, is much better than expected from Doppler gradients. Thus, calculation of a patient/prosthesis mismatch can be misleading.
Authors:
G Dohmen; C Schmitz; U Steinseifer; N Hatam; R D Hilgers; R Autschbach; J Spillner
Related Documents :
21132799 - Acute coronary occlusion following tavi.
21872209 - Costs and quality of life associated with radial artery and saphenous vein cardiac bypa...
19444569 - Anesthetic management for severe aortic regurgitation in an infant repaired by ross pro...
21457999 - Primary sutureless repair for "simple" total anomalous pulmonary venous connection: mid...
19584069 - Apico-aortic conduit for aortic stenosis with a porcelain aorta; technical modification...
21440159 - Isolated rupture of the right upper pulmonary vein: a blunt cardiac trauma case.
3993849 - Management of the tortuous internal carotid artery.
21573809 - Early and long-term outcome of surgically treated giant internal carotid artery aneurys...
21155999 - Idiopathic pulmonary artery aneurysm.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-5-3
Journal Detail:
Title:  The Thoracic and cardiovascular surgeon     Volume:  -     ISSN:  1439-1902     ISO Abbreviation:  -     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-5-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7903387     Medline TA:  Thorac Cardiovasc Surg     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© Georg Thieme Verlag KG Stuttgart · New York.
Affiliation:
Department of Thoracic and Cardiovascular Surgery, University Hospital Aachen, Medical Faculty RWTH, Aachen, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  The Dilemma of Subaortic Stenosis - A Single Center Experience of 15 Years with a Review of the Lite...
Next Document:  Long-term Results of Mechanical and Biological Heart Valves in Dialysis and Non-Dialysis Patients.