Document Detail

Influence of Aloe arborescens Mill. Extract on Selected Parameters of Prooxidant-Antioxidant Equilibrium and Cytokine Synthesis in Rowers.
MedLine Citation:
PMID:  23349254     Owner:  NLM     Status:  Publisher    
This investigation examined the effect of supplementation with Biostimine® (extract from Aloe arborescens Mill. leaves) on the levels of prooxidant- antioxidant equilibrium markers and anti- and pro-inflammatory cytokines in rowers subjected to exhaustive exercise. This double-blind study included 18 members of the Polish Rowing Team. Subjects were randomly assigned to the supplemented group (n = 9), which received one ampoule of Biostimine® once daily for 4 weeks, or to the placebo group (n = 9). Subjects performed a 2000-meter maximum test on a rowing ergometer at the beginning and at the end of the preparatory camp. Blood samples were obtained from the antecubital vein prior to each exercise test, one minute after completing the test, and after a 24-hour recovery period. Superoxide dismutase and glutathione peroxidase activity, as well as the concentration of thiobarbituric acid reactive substances (TBARS) were assessed in erythrocytes. Additionally, total antioxidant capacity (TAC) and creatine kinase activity were measured in plasma samples, and cytokine (IL-6, IL-10) concentrations were determined in the serum. Before and after Biostimine® supplementation, exercise significantly increased the values of SOD, IL-6, IL-10, and TBARS in both groups. However, post-exercise and recovery levels of TBARS were significantly lower in athletes receiving Biostimine® than in controls. After supplementation, TAC was the only variable with the level being significantly higher in the supplemented group than in the placebo group. Consequently, we can conclude that Biostimine® supplementation reduces the post-exercise level of TBARS by increasing the antioxidant activity of plasma, but has no effect on inflammatory markers.
Piotr Basta; Lucja Pilaczynska-Szczesniak; Donata Woitas-Slubowska; Anna Skarpanska-Stejnborn
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-23
Journal Detail:
Title:  International journal of sport nutrition and exercise metabolism     Volume:  -     ISSN:  1543-2742     ISO Abbreviation:  Int J Sport Nutr Exerc Metab     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100939812     Medline TA:  Int J Sport Nutr Exerc Metab     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Water Sports, University School of Physical Education in Poznañ, Branch in Gorzów Wlkp., Gorzów Wlkp., Poland.
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